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BMP10 Protein (Bone Morphogenetic Protein 10)

BMP10 Spezies: Human Wirt: HEK-293 Cells Recombinant > 95 % as determined by SDS-PAGE and Coomassie blue staining AbP, Func, PI, STD Active
Produktnummer ABIN2715288
$388.80
Zzgl. Versandkosten $45.00 und $20.00 Trockeneis
10 μg
Lieferung in 4 bis 8 Werktagen
  • Target Alle BMP10 Proteine anzeigen
    BMP10 (Bone Morphogenetic Protein 10 (BMP10))
    Protein-Typ
    Recombinant
    Biologische Aktivität
    Active
    Spezies
    • 6
    • 4
    • 1
    Human
    Quelle
    • 5
    • 2
    • 2
    • 1
    • 1
    HEK-293 Cells
    Applikation
    Antibody Production (AbP), Functional Studies (Func), Protein Interaction (PI), Standard (STD)
    Spezifität
    Optimal preservation of protein structure, post-translational modifications and functions.
    Produktmerkmale
    • Recombinant human BMP10 protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    • Tested for bioactivity.
    Reinheit
    > 95 % as determined by SDS-PAGE and Coomassie blue staining
    Endotoxin-Niveau
    Endotoxin level is <0.1 ng/μg of protein (<1EU/μg).
    Biological Activity Comment
    Determined by its ability to induce alkaline phosphatase production by ATDC-5 cells. The expected ED50 for this effect is 4.0-6.0 ng/ml.
  • Applikationshinweise
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Protein-protein interaction
    In vitro biochemical assays and cell-based functional assays
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Buffer
    Lyophilized from a 0.2 μM filtered solution of 20 mM phosphate buffer,100 mM NaCl, pH 7.2
    Handhabung
    Resuspend the protein in the desired concentration in proper buffer
    Lagerung
    -80 °C
    Informationen zur Lagerung
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target
    BMP10 (Bone Morphogenetic Protein 10 (BMP10))
    Andere Bezeichnung
    Bmp10 (BMP10 Produkte)
    Synonyme
    BMP10, si:dkey-13n15.5, Bmp10, BMP9, BMP-10, bone morphogenetic protein 10, BMP10, bmp10, LOC662386, Bmp10
    Hintergrund
    This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate the mature protein, which binds to the activin receptor-like kinase 1 (ALK1) and plays important roles in cardiovascular development including cardiomyocyte proliferation and regulation of heart size, closure of the ductus arteriosus, angiogenesis and ventricular trabeculation.
    Molekulargewicht
    24.4 kDa
    NCBI Accession
    NP_055297
    Pathways
    Hormone Activity, Regulation of Muscle Cell Differentiation
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