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ATP6V0E1 Protein (ATPase, H+ Transporting, Lysosomal 9kDa, V0 Subunit E1) (Myc-DYKDDDDK Tag)

ATP6V0E1 Spezies: Human Wirt: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Produktnummer ABIN2715054
$1,112.40
Zzgl. Versandkosten $45.00 und $20.00 Trockeneis
20 μg
Lieferung in 16 Werktagen
  • Target Alle ATP6V0E1 Proteine anzeigen
    ATP6V0E1 (ATPase, H+ Transporting, Lysosomal 9kDa, V0 Subunit E1 (ATP6V0E1))
    Protein-Typ
    Recombinant
    Spezies
    Human
    Quelle
    • 1
    • 1
    HEK-293 Cells
    Aufreinigungstag / Konjugat
    Dieses ATP6V0E1 Protein ist gelabelt mit Myc-DYKDDDDK Tag.
    Applikation
    Antibody Production (AbP), Standard (STD)
    Produktmerkmale
    • Recombinant human ATP6V0E1 protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    Reinheit
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
  • Applikationshinweise
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Kommentare

    The tag is located at the C-terminal.

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    50 μg/mL
    Buffer
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    Lagerung
    -80 °C
    Informationen zur Lagerung
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target
    ATP6V0E1 (ATPase, H+ Transporting, Lysosomal 9kDa, V0 Subunit E1 (ATP6V0E1))
    Andere Bezeichnung
    Atp6v0e1 (ATP6V0E1 Produkte)
    Synonyme
    ATP6H, ATP6V0E, M9.2, Vma21, Vma21p, Atp6k, Atp6v0e1, Atp6v0e, Dsr-1A, dsr-1, ATPase H+ transporting V0 subunit e1, ATPase, H+ transporting, lysosomal V0 subunit E, ATP6V0E1, Atp6v0e, Atp6v0e1
    Hintergrund
    This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c', c', and d. Additional isoforms of many of the V1 and V0 subunit proteins are encoded by multiple genes or alternatively spliced transcript variants. This encoded protein is possibly part of the V0 subunit. Since two nontranscribed pseudogenes have been found in dog, it is possible that the localization to chromosome 2 for this gene by radiation hybrid mapping is representing a pseudogene. Genomic mapping puts the chromosomal location on 5q35.3.
    Molekulargewicht
    9.2 kDa
    NCBI Accession
    NP_003936
    Pathways
    Transition Metal Ion Homeostasis, Proton Transport
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