ATP6V0A4 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)
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- Target Alle ATP6V0A4 Proteine anzeigen
- ATP6V0A4 (ATPase, H+ Transporting, Lysosomal V0 Subunit A4 (ATP6V0A4))
- Protein-Typ
- Recombinant
- Proteineigenschaft
- Transcript Variant 1
- Spezies
- Human
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Quelle
- HEK-293 Cells
- Aufreinigungstag / Konjugat
- Dieses ATP6V0A4 Protein ist gelabelt mit Myc-DYKDDDDK Tag.
- Applikation
- Antibody Production (AbP), Standard (STD)
- Produktmerkmale
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- Recombinant human ATP6V0A4 (transcript variant 1) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Reinheit
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product ATP6V0A4 Protein
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- Applikationshinweise
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Kommentare
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The tag is located at the C-terminal.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Lagerung
- -80 °C
- Informationen zur Lagerung
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- ATP6V0A4 (ATPase, H+ Transporting, Lysosomal V0 Subunit A4 (ATP6V0A4))
- Andere Bezeichnung
- Atp6v0a4 (ATP6V0A4 Produkte)
- Synonyme
- A4 Protein, ATP6N1B Protein, ATP6N2 Protein, RDRTA2 Protein, RTA1C Protein, RTADR Protein, STV1 Protein, VPH1 Protein, VPP2 Protein, Atp6n1b Protein, a4 Protein, ATPase H+ transporting V0 subunit a4 Protein, ATPase, H+ transporting, lysosomal V0 subunit A4 Protein, ATP6V0A4 Protein, Atp6v0a4 Protein
- Hintergrund
- This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of intracellular compartments of eukaryotic cells. V-ATPase dependent acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c', c'', and d. This gene is one of four genes in man and mouse that encode different isoforms of the a subunit. Alternatively spliced transcript variants encoding the same protein have been described. Mutations in this gene are associated with renal tubular acidosis associated with preserved hearing.
- Molekulargewicht
- 96.2 kDa
- NCBI Accession
- NP_065683
- Pathways
- Sensory Perception of Sound, Transition Metal Ion Homeostasis, Proton Transport
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