ARPC1B Protein (Actin Related Protein 2/3 Complex, Subunit 1B, 41kDa) (Myc-DYKDDDDK Tag)

Produktnummer ABIN2714939

Produktdetails

Target: ARPC1B (Actin Related Protein 2/3 Complex, Subunit 1B, 41kDa (ARPC1B))

Protein-Typ: Recombinant

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses ARPC1B Protein ist gelabelt mit Myc-DYKDDDDK Tag.

Applikation: Antibody Production (AbP), Standard (STD)

Produktmerkmale:

• Recombinant human ARPC1B / ARC41 protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Reinheit: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Anwendungsinformationen

Applikationshinweise: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Kommentare:

The tag is located at the C-terminal.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Lagerung: -80 °C

Informationen zur Lagerung: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Antigendetails

Target: ARPC1B (Actin Related Protein 2/3 Complex, Subunit 1B, 41kDa (ARPC1B))

Andere Bezeichnung: Arpc1b,arc41 (ARPC1B Produkte)

Synonyme: ARC41, p40-ARC, p41-ARC, cb871, arpc1a, fj15h02, zgc:64056, wu:fj08e12, wu:fj15h02, 41kDa, AA408064, AA408534, AA571392, AF007010, AW208418, L72, SOP2Hs, ACTIN-RELATED PROTEIN C1, ARPC1, F16D14.14, F16D14_14, actin-related protein C1B, arc41, p40-arc, p41-arc, actin related protein 2/3 complex subunit 1B, actin related protein 2/3 complex, subunit 1B, ARP2/3 complex 41 kDa subunit, actin-related protein C1B, actin-related protein 2/3 complex subunit 1B, actin related protein 2/3 complex subunit 1B S homeolog, ARPC1B, Arpc1b, EHI_094120, arpc1b, LOC100410640, arpc1b.S

Hintergrund: This gene encodes one of seven subunits of the human Arp2/3 protein complex. This subunit is a member of the SOP2 family of proteins and is most similar to the protein encoded by gene ARPC1A. The similarity between these two proteins suggests that they both may function as p41 subunit of the human Arp2/3 complex that has been implicated in the control of actin polymerization in cells. It is possible that the p41 subunit is involved in assembling and maintaining the structure of the Arp2/3 complex. Multiple versions of the p41 subunit may adapt the functions of the complex to different cell types or developmental stages. This protein also has a role in centrosomal homeostasis by being an activator and substrate of the Aurora A kinase.

Molekulargewicht: 40.8 kDa

NCBI Accession: NP_005711

Pathways: RTK Signalweg, Regulation of Actin Filament Polymerization