ARFGAP1 Protein (ADP-Ribosylation Factor GTPase Activating Protein 1) (Transcript Variant 2) (Myc-DYKDDDDK Tag)

Produktnummer ABIN2714861

Produktdetails

Target: ARFGAP1 (ADP-Ribosylation Factor GTPase Activating Protein 1 (ARFGAP1))

Protein-Typ: Recombinant

Proteineigenschaft: Transcript Variant 2

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses ARFGAP1 Protein ist gelabelt mit Myc-DYKDDDDK Tag.

Applikation: Antibody Production (AbP), Standard (STD)

Produktmerkmale:

• Recombinant human ARFGAP1 (transcript variant 2) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Reinheit: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Anwendungsinformationen

Applikationshinweise: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Kommentare:

The tag is located at the C-terminal.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Lagerung: -80 °C

Informationen zur Lagerung: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Antigendetails

Target: ARFGAP1 (ADP-Ribosylation Factor GTPase Activating Protein 1 (ARFGAP1))

Andere Bezeichnung: Arfgap1 (ARFGAP1 Produkte)

Synonyme: ARF1GAP, HRIHFB2281, AI115377, Arf1gap, Arf GAP1, arf1gap, atfb1, atfb3, jlns1, k(v)7.1, kcna8, kcna9, kv1.9, kv7.1, kvlqt1, lqt, lqt1, rws, sqt2, wrs, ARFGAP3, ADP ribosylation factor GTPase activating protein 1, ADP-ribosylation factor GTPase activating protein 1, ADP ribosylation factor GTPase activating protein 1 S homeolog, putative ADP-ribosylation factor GTPase activating protein 1, ATP-dependent RNA helicase DBP9, ARFGAP1, Arfgap1, arfgap1.S, Tb11.01.6060, arfgap1, LMJF_32_1230, MGYG_02419

Hintergrund: The protein encoded by this gene is a GTPase-activating protein, which associates with the Golgi apparatus and which interacts with ADP-ribosylation factor 1. The encoded protein promotes hydrolysis of ADP-ribosylation factor 1-bound GTP and is required for the dissociation of coat proteins from Golgi-derived membranes and vesicles. Dissociation of the coat proteins is required for the fusion of these vesicles with target compartments. The activity of this protein is stimulated by phosphoinosides and inhibited by phosphatidylcholine. Alternative splicing results in multiple transcript variants.

Molekulargewicht: 45.5 kDa

NCBI Accession: NP_783202

Pathways: p53 Signalweg, ER-Nucleus Signaling, Unfolded Protein Response