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APEX1 Protein (Apurinic/Apyrimidinic Endonuclease 1) (Transcript Variant 3) (Myc-DYKDDDDK Tag)

APEX1 Spezies: Human Wirt: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Produktnummer ABIN2714787
$1,112.40
Zzgl. Versandkosten $45.00 und $20.00 Trockeneis
20 μg
Lieferung in 11 Werktagen
  • Target Alle APEX1 Proteine anzeigen
    APEX1 (Apurinic/Apyrimidinic Endonuclease 1 (APEX1))
    Protein-Typ
    Recombinant
    Proteineigenschaft
    Transcript Variant 3
    Spezies
    • 12
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Quelle
    • 8
    • 7
    • 4
    • 2
    • 1
    HEK-293 Cells
    Aufreinigungstag / Konjugat
    Dieses APEX1 Protein ist gelabelt mit Myc-DYKDDDDK Tag.
    Applikation
    Antibody Production (AbP), Standard (STD)
    Produktmerkmale
    • Recombinant human APEX1 / REF-1 (transcript variant 3) protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    Reinheit
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
  • Applikationshinweise
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Kommentare

    The tag is located at the C-terminal.

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    50 μg/mL
    Buffer
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    Lagerung
    -80 °C
    Informationen zur Lagerung
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target
    APEX1 (Apurinic/Apyrimidinic Endonuclease 1 (APEX1))
    Andere Bezeichnung
    Apex1,ref-1 (APEX1 Produkte)
    Synonyme
    apex1, MGC76280, MGC79645, MGC78928, APE, APE1, APEN, APEX, APX, HAP1, REF1, Apex, REF-1, BAP1, apex1a, hm:zehn1532, wu:fc13d11, zgc:66204, Ref-1, apurinic/apyrimidinic endodeoxyribonuclease 1, APEX nuclease (multifunctional DNA repair enzyme) 1, APEX nuclease (multifunctional DNA repair enzyme) 1 L homeolog, DNA-(apurinic or apyrimidinic site) lyase, apurinic/apyrimidinic endonuclease 1, APEX1, apex1, apex1.L, CNG03640, CNH01280, nth, Spirs_4119, Palpr_0103, Apex1
    Hintergrund
    Apurinic/apyrimidinic (AP) sites occur frequently in DNA molecules by spontaneous hydrolysis, by DNA damaging agents or by DNA glycosylases that remove specific abnormal bases. AP sites are pre-mutagenic lesions that can prevent normal DNA replication so the cell contains systems to identify and repair such sites. Class II AP endonucleases cleave the phosphodiester backbone 5' to the AP site. This gene encodes the major AP endonuclease in human cells. Splice variants have been found for this gene all encode the same protein.
    Molekulargewicht
    35.4 kDa
    NCBI Accession
    NP_542380
    Pathways
    DNA Reparatur, Chromatin Binding, Cell RedoxHomeostasis, Smooth Muscle Cell Migration, Positive Regulation of Response to DNA Damage Stimulus
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