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ACTN1 Protein (Actinin, alpha 1) (Transcript Variant 2) (Myc-DYKDDDDK Tag)

ACTN1 Spezies: Human Wirt: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Produktnummer ABIN2714612
$1,112.40
Zzgl. Versandkosten $45.00 und $20.00 Trockeneis
20 μg
Lieferung in 11 Werktagen
  • Target Alle ACTN1 Proteine anzeigen
    ACTN1 (Actinin, alpha 1 (ACTN1))
    Protein-Typ
    Recombinant
    Proteineigenschaft
    Transcript Variant 2
    Spezies
    • 6
    • 1
    • 1
    Human
    Quelle
    • 3
    • 2
    • 2
    • 1
    HEK-293 Cells
    Aufreinigungstag / Konjugat
    Dieses ACTN1 Protein ist gelabelt mit Myc-DYKDDDDK Tag.
    Applikation
    Antibody Production (AbP), Standard (STD)
    Produktmerkmale
    • Recombinant human Alpha-actinin-1 / ACTN1 (transcript variant 2) protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    Reinheit
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
  • Applikationshinweise
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Kommentare

    The tag is located at the C-terminal.

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    50 μg/mL
    Buffer
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    Lagerung
    -80 °C
    Informationen zur Lagerung
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target
    ACTN1 (Actinin, alpha 1 (ACTN1))
    Andere Bezeichnung
    alpha-Actinin-1,actn1 (ACTN1 Produkte)
    Synonyme
    ACTN1, actinin, BDPLT15, 3110023F10Rik, Actn1a, actinin alpha 1, actinin, alpha 1, actinin alpha 1 L homeolog, ACTN1, actn1, Actn1, actn1.L
    Hintergrund
    Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. This gene encodes a nonmuscle, cytoskeletal, alpha actinin isoform and maps to the same site as the structurally similar erythroid beta spectrin gene. Three transcript variants encoding different isoforms have been found for this gene.
    Molekulargewicht
    102.9 kDa
    NCBI Accession
    NP_001093
    Pathways
    Cell-Cell Junction Organization
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