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F11R Protein

Dieses Recombinant F11R-Protein wird in HEK-293 Cells exprimiert.
Produktnummer ABIN2713651

Kurzübersicht für F11R Protein (ABIN2713651)

Target

Alle F11R Proteine anzeigen
F11R (F11 Receptor (F11R))

Protein-Typ

Recombinant

Spezies

  • 14
  • 5
  • 5
  • 2
  • 1
  • 1
  • 1
Human

Quelle

  • 11
  • 8
  • 3
  • 2
  • 1
HEK-293 Cells

Applikation

Antibody Production (AbP), Standard (STD)

Reinheit

> 95 % as determined by SDS-PAGE and Coomassie blue staining
  • Produktmerkmale

    • Recombinant human CD321 / JAM1 protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone

    Endotoxin-Niveau

    < 0.1 EU per μg protein as determined by LAL test
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  • Applikationshinweise

    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Buffer

    Lyophilized from a 0.2 μM filtered solution of 20 mM Tris-HCl, 50 mM NaCl, 100 mM Glycine, pH 7.5. Stable for at least 6 months from date of receipt under proper storage and handling conditions.

    Lagerung

    -80 °C

    Informationen zur Lagerung

    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target

    F11R (F11 Receptor (F11R))

    Andere Bezeichnung

    Cd321,jam1

    Hintergrund

    Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. The protein encoded by this immunoglobulin superfamily gene member is an important regulator of tight junction assembly in epithelia. In addition, the encoded protein can act as (1) a receptor for reovirus, (2) a ligand for the integrin LFA1, involved in leukocyte transmigration, and (3) a platelet receptor. Multiple 5&apos alternatively spliced variants, encoding the same protein, have been identified but their biological validity has not been established.

    Molekulargewicht

    23.9 kDa

    NCBI Accession

    NP_058642

    Pathways

    Cell-Cell Junction Organization
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