F11R Protein
Kurzübersicht für F11R Protein (ABIN2713651)
Target
Alle F11R Proteine anzeigenProtein-Typ
Spezies
Quelle
Applikation
Reinheit
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Produktmerkmale
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- Recombinant human CD321 / JAM1 protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
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Endotoxin-Niveau
- < 0.1 EU per μg protein as determined by LAL test
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Applikationshinweise
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Buffer
- Lyophilized from a 0.2 μM filtered solution of 20 mM Tris-HCl, 50 mM NaCl, 100 mM Glycine, pH 7.5. Stable for at least 6 months from date of receipt under proper storage and handling conditions.
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Lagerung
- -80 °C
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Informationen zur Lagerung
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- F11R (F11 Receptor (F11R))
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Andere Bezeichnung
- Cd321,jam1
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Hintergrund
- Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. The protein encoded by this immunoglobulin superfamily gene member is an important regulator of tight junction assembly in epithelia. In addition, the encoded protein can act as (1) a receptor for reovirus, (2) a ligand for the integrin LFA1, involved in leukocyte transmigration, and (3) a platelet receptor. Multiple 5&apos alternatively spliced variants, encoding the same protein, have been identified but their biological validity has not been established.
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Molekulargewicht
- 23.9 kDa
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NCBI Accession
- NP_058642
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Pathways
- Cell-Cell Junction Organization
Target
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