Determined by the inhibitory effect on monocyte migration response to human MIP - 1 alpha using a concentration range of 1.0 μg - 10.0 μg/mL of viral MIP - 2 will inhibit 25 ng/mL of human MIP - 1 alpha.
Reinheit
< 98 % by SDS-PAGE gel and HPLC analyses.
Endotoxin-Niveau
Endotoxin level is less than 0.1 ng per μg (1 EU/μg).
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Lyophilized
Handhabung
As with any protein, exposing Viral MIP-2 recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.
Lagerung
-20 °C
Informationen zur Lagerung
The recombinant protein is stable for at least 2 years from date of receipt at -20 °C. Reconstituted Viral MIP-2 is stable for at least 3 months when stored in working aliquots with a carrier protein at -20 °C.
Haltbarkeit
24 months
Target
Viral MIP-2
Substanzklasse
Viral Protein
Hintergrund
VMIP-2 is a chemokine analog encoded by human herpes virus, and has been shown to have antagonist activity towards several chemokine receptors. Recombinant vMIP-2 is a 7.9 kDa protein consisting of 70 amino acids including the four highly conserved cysteine residues present in CC chemokines.