Resistin Protein (RETN)
Kurzübersicht für Resistin Protein (RETN) (ABIN2469024)
Target
Alle Resistin (RETN) Proteine anzeigenProtein-Typ
Spezies
Quelle
Reinheit
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Sequenz
- SSMPLCPIDE AIDKKIKQDF NSLFPNAIKN IGLNCWTVSS RGKLASCPEG TAVLSCSCGS ACGSWDIREE KVCHCQCARI DWTAARCCKL QVAS
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Endotoxin-Niveau
- Endotoxin level is less than 0.1 ng per μg (1 EU/μg).
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Resistin (RETN) (Active) protein
RETN Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant >95 % as determined by SDS-PAGE Func Active
Resistin (RETN) (AA 17-108) protein (Fc Tag)RETN Spezies: Human Wirt: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Resistin (RETN) (AA 21-114) protein (Fc Tag)RETN Spezies: Maus Wirt: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Resistin (RETN) (AA 16-108) protein (His tag)RETN Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Resistin (RETN) (AA 1-108) protein (GST tag)RETN Spezies: Human Wirt: Wheat germ Recombinant WB, ELISA, AP, AA
Resistin (RETN) (AA 19-108) protein (Fc Tag)RETN Spezies: Human Wirt: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
Resistin (RETN) protein (Myc-DYKDDDDK Tag)RETN Spezies: Human Wirt: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Handhabung
- As with any protein, exposing Resistin recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- The recombinant protein is stable for at least 2 years from date of receipt at -20 °C. Reconstituted Resistin is stable for at least 3 months when stored in working aliquots with a carrier protein at -20 °C.
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Haltbarkeit
- 24 months
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- Resistin (RETN)
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Andere Bezeichnung
- Resistin
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Hintergrund
- Resistin belongs to a family of tissue-specific cytokines termed FIZZ (found in inflammatory zones) and RELM. The three known members of this family , Resistin, RELM-alpha and RELM-beta share a highly conserved C-terminal domain, characterized by 10 cysteine residues with a unique spacing motif of C-X11-C-X8-C-X-C-X3-C-X10-C-X-C-X-C-X9-C-C. Resistin is an adipose-derived cytokine (adipokine) whose physiological function and molecular targets are largely unknown. Studies have shown that Resistin suppresses insulin's ability to stimulate glucose uptake, and postulated that Resistin might be an important link between obesity and Type 2 diabetes. Other studies have indicated that Resistin expression is severely suppressed in obesity and that it may act as a feedback regulator of Adipogenesis. Recombinant murine Resistin is a 20.2 kDa disulfide-linked homodimeric protein composed of two identical 94 amino acid chains linked by a single disulfide bond.
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Gen-ID
- 57264
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NCBI Accession
- NP_001191888
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OMIM
- 326368221
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UniProt
- Q99P87
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Pathways
- Feeding Behaviour, Smooth Muscle Cell Migration
Target
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