MSTN Protein (Propeptide)

Produktnummer ABIN2468877

Dieses Recombinant MSTN-Protein wird in Escherichia coli (E. coli) exprimiert.

Kurzübersicht für MSTN Protein (Propeptide) (ABIN2468877)

Target: MSTN (Myostatin (MSTN))

Protein-Typ: Recombinant

Biologische Aktivität: Active

Spezies: Human

Quelle: Escherichia coli (E. coli)

Reinheit: < 98 % by SDS-PAGE gel and HPLC analyses.

Produktdetails

Proteineigenschaft: Propeptide

Sequenz: MNENSEQKEN VEKEGLCNAC TWRQNTKSSR IEAIKIQILS KLRLETAPNI SKDVIRQLLP KAPPLRELID QYDVQRDDSS DGSLEDDDYH ATTETIITMP TESDFLMQVD GKPKCCFFKF SSKIQYNKVV KAQLWIYLRP VETPTTVFVQ ILRLIKPMKD GTRYTGIRSL KLDMNPGTGI WQSIDVKTVL QNWLKQPESN LGIEIKALDE NGHDLAVTFP GPGEDGLNPF LEVKVTDTPK RSRR

Produktmerkmale: Biological activity was determined by its ability to neutralize the Myostatin inhibitory effect of murine MPC - 11 cells. The expected ED50is 0.01 - 0.04 μg/mL in the presence of 50 ng/mL Myostatin.

Endotoxin-Niveau: Endotoxin level is less than 0.1 ng per μg (1 EU/μg).

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Handhabung: As with any protein, exposing Myostatin Propeptide recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.

Lagerung: -20 °C

Informationen zur Lagerung: The recombinant protein is stable for at least 2 years from date of receipt at -20 °C. Reconstituted Myostatin Propeptide is stable for at least 3 months when stored in working aliquots with a carrier protein at -20 °C.

Haltbarkeit: 24 months

Antigendetails

Target: MSTN (Myostatin (MSTN))

Andere Bezeichnung: Myostatin

Hintergrund: Mature Myostatin is obtained by proteolytic processing of a biologically-inactive precursor protein, which contains an N-terminal propeptide of 243 amino acid residues. Myostatin Propeptide exhibits high binding affinity for myostatin and has been shown to be a potent inhibitor of Myostatin. Over-expression of myostatin propeptide in mice resulted in large increases (up to 200 % ) in skeletal muscle mass, similar to those observed in Myostatin knockout mice. Recombinant Human Myostatin Propeptide is a 27.8 kDa protein consisting of 244 amino acid residues.

Gen-ID: 2660

NCBI Accession: NP_005250

OMIM: 4885259

UniProt: O14793