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GDF7 Protein

Recombinant GDF7-Protein exprimiert in Escherichia coli (E. coli).
Produktnummer ABIN2468476

Kurzübersicht für GDF7 Protein (ABIN2468476)

Target

Alle GDF7 Proteine anzeigen
GDF7 (Growth Differentiation Factor 7 (GDF7))

Protein-Typ

Recombinant

Biologische Aktivität

Active

Spezies

  • 3
  • 2
  • 1
  • 1
Human

Quelle

  • 6
  • 1
Escherichia coli (E. coli)

Reinheit

< 98 % by SDS-PAGE gel and HPLC analyses.
  • Sequenz

    TALAGTRTAQ GSGGGAGRGH GRRGRSRCSR KPLHVDFKEL GWDDWIIAPL DYEAYHCEGL CDFPLRSHLE PTNHAIIQTL LNSMAPDAAP ASCCVPARLS PISILYIDAA NNVVYKQYED MVVEACGCR

    Produktmerkmale

    Biological activity was determined by its ability to inhibit induced alkaline phosphatase production by ATDC-5 chondrogenic cells.
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  • Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Handhabung

    As with any protein, exposing GDF-7 recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    The recombinant protein is stable for at least 2 years from date of receipt at -20 °C. Reconstituted GDF-7 stable for at least 3 months when stored in working aliquots with a carrier protein at -20 °C.

    Haltbarkeit

    24 months
  • Target

    GDF7 (Growth Differentiation Factor 7 (GDF7))

    Andere Bezeichnung

    GDF-7

    Hintergrund

    GDF-7 belongs to the TGF-beta superfamily of growth and differentiation factors. It is expressed selectively by roof plate cells that are located in the developing embryonic central nervous system, and has been shown to influence the neuronal identity of cells within the central nervous system. GDF-7 has also been implicated in the formation, maintenance, and repair of certain cartilage and ligament tissue. Recombinant human GDF-7 is a 28 kDa disulfide linked homodimer containing two 129 amino acid residues.

    Gen-ID

    151449

    NCBI Accession

    NP_878248

    OMIM

    61835232

    UniProt

    Q7Z4P5

    Pathways

    Tube Formation
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