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Vascular Cell Adhesion Molecule 1 (VCAM1) (AA 25-697) protein (His tag) Protein

VCAM1 Spezies: Human Wirt: HEK-293 Cells Recombinant >92 % as determined by SDS-PAGE.
Produktnummer ABIN2181894
$275.00
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  • Target Alle VCAM1 Proteine anzeigen
    VCAM1
    Protein-Typ
    Recombinant
    Proteineigenschaft
    AA 25-697
    Spezies
    • 21
    • 7
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    Human
    Quelle
    • 19
    • 7
    • 4
    • 3
    • 2
    • 2
    • 2
    HEK-293 Cells
    Aufreinigungstag / Konjugat
    Dieses VCAM1 Protein ist gelabelt mit His tag.
    Sequenz
    AA 25-697
    Produktmerkmale
    This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 75 kDa. The protein migrates as 80-115 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
    Reinheit
    >92 % as determined by SDS-PAGE.
    Sterilität
    0.22 μm filtered
    Endotoxin-Niveau
    Less than 1.0 EU per μg by the LAL method.
  • Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Buffer
    PBS, pH 7.4
    Handhabung
    Please avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    No activity loss was observed after storage at: In lyophilized state for 1 year (4 °C-8 °C), After reconstitution under sterile conditions for 1 month (4 °C-8 °C) or 3 months (-20 °C to -70 °C).
  • Target
    VCAM1
    Andere Bezeichnung
    VCAM-1 (VCAM1 Produkte)
    Synonyme
    CD106, INCAM-100, Vcam-1, VCAM1B, fi76d06, wu:fi76d06, zgc:158875, VCAM1, vascular cell adhesion molecule 1, vascular cell adhesion molecule 1b, VCAM1, Vcam1, vcam1b, VCAM-1
    Hintergrund
    Vascular cell adhesion protein 1 (VCAM1) is also known as CD106, INCAM-100 and L1CAM, is a cell surface sialoglycoprotein belonging to the immunoglobulin superfamily. VCAM1 / CD106 contains 7 Ig-like C2-type (immunoglobulin-like) domains. CD106 / VCAM-1 is expressed on inflammed vascular endothelium, as well as on macrophage-like and dendritic cell types in both normal and inflammed tissue. L1CAM / VCAM-1 is Important in cell-cell recognition and appears to function in leukocyte-endothelial cell adhesion. CD106 / VCAM1 interacts with the beta-1 integrin VLA4 on leukocytes, and mediates both adhesion and signal transduction. The VCAM1 / VLA4 interaction may play a pathophysiologic role both in immune responses and in leukocyte emigration to sites of inflammation. INCAM-100 / VCAM1 binds to ECMV-D capsid proteins and acts as a receptor for this virus.
    Molekulargewicht
    74.9 kDa
    NCBI Accession
    NP_001069
    Pathways
    Carbohydrate Homeostasis
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