PLAUR Protein (AA 23-303) (His tag)

Produktnummer ABIN2181889

Produktdetails

Target: PLAUR (Plasminogen Activator, Urokinase Receptor (PLAUR))

Protein-Typ: Recombinant

Proteineigenschaft: AA 23-303

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses PLAUR Protein ist gelabelt mit His tag.

Sequenz: AA 23-303

Produktmerkmale: This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 32.1 kDa. The protein migrates as 44-48 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

Reinheit: >92 % as determined by SDS-PAGE.

Sterilität: 0.22 μm filtered

Endotoxin-Niveau: Less than 1.0 EU per μg by the LAL method.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: PBS, pH 7.4

Handhabung: Please avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: No activity loss was observed after storage at: In lyophilized state for 1 year (4 °C), After reconstitution under sterile conditions for 3 months (-70 °C).

Antigendetails

Target: PLAUR (Plasminogen Activator, Urokinase Receptor (PLAUR))

Andere Bezeichnung: uPAR (PLAUR Produkte)

Synonyme: Cd87 Protein, u-PAR Protein, uPAR Protein, CD87 Protein, U-PAR Protein, UPAR Protein, URKR Protein, Par Protein, Plaur3 Protein, uPAR-2 Protein, uPAR-3 Protein, PLAUR Protein, plasminogen activator, urokinase receptor Protein, Plaur Protein, PLAUR Protein

Hintergrund: Urokinase plasminogen activator surface receptor (U-PAR) is also known as PLAUR, Monocyte activation antigen Mo3, CD antigen CD87. PLAUR contains three UPAR/Ly6 domains. U-PAR is expressed in neurons of the rolandic area of the brain (at protein level) and is also expressed in the brain. PLAUR / CD87 interacts with MRC2, SRPX2 and SORL1. PLAUR / UPAR acts as a receptor for urokinase plasminogen activator and plays a role in localizing and promoting plasmin formation. U-PAR mediates the proteolysis-independent signal transduction activation effects of U-PA.

Molekulargewicht: 32.3 kDa

Pathways: Inositol Metabolic Process