Hemagglutinin Protein (HA) (AA 19-338, AA 341-523) (Fc Tag)

Produktnummer ABIN2181208

Dieses Recombinant Hemagglutinin-Protein wird in HEK-293 Cells produziert.

Kurzübersicht für Hemagglutinin Protein (HA) (AA 19-338, AA 341-523) (Fc Tag) (ABIN2181208)

Target: Hemagglutinin (HA)

Protein-Typ: Recombinant

Spezies: Influenza Virus

Quelle: HEK-293 Cells

Reinheit: >95 % as determined by SDS-PAGE.

Produktdetails

Proteineigenschaft: AA 19-338, AA 341-523

Virus Strain: A/Shanghai/2/2013

Aufreinigungstag / Konjugat: Dieses Hemagglutinin Protein ist gelabelt mit Fc Tag.

Sequenz: AA 19-338,AA 341-523

Produktmerkmale: This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 84.5 kDa. The protein migrates as 110-120 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

Sterilität: 0.22 μm filtered

Endotoxin-Niveau: Less than 1.0 EU per μg by the LAL method.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: 50 mM Tris, 100 mM Glycine, pH 7.5

Handhabung: Please avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: No activity loss was observed after storage at: In lyophilized state for 1 year (4 °C), After reconstitution under sterile conditions for 3 months (-70 °C).

Antigendetails

Target: Hemagglutinin (HA)

Substanzklasse: Influenza Protein

Hintergrund: Influenza, commonly known as "the flu", is an infectious disease of birds and mammals caused by RNA viruses of the family Orthomyxoviridae, the influenza viruses. The virus is divided into three main types (Influenzavirus A, Influenzavirus B, and Influenzavirus C), which are distinguished by differences in two major internal proteins (hemagglutinin (HA) and neuraminidase (NA), which are the most important targets for the immune system. The type A viruses are the most virulent human pathogens among the three influenza types and cause the most severe disease. The serotypes that have been confirmed in humans, ordered by the number of known human pandemic deaths, are: H1N1, H2N2, H3N2, H5N1, H7N7, H1N2, H9N2, H7N2, H7N3, H10N7, H7N9. H7N9 is a serotype of the species Influenzavirus A (avian influenza virus or bird flu virus). H7 normally circulates amongst avian populations with some variants known to occasionally infect humans. An H7N9 virus was first reported to have infected humans in 2013 in China.

Molekulargewicht: 82.5 kDa

Gen-ID: 18, 17