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Epithelial Cell Adhesion Molecule (EPCAM) (AA 24-265) protein (His tag)

EPCAM Spezies: Rhesusaffen Wirt: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE.
Produktnummer ABIN2181021
$385.00
Zzgl. Versandkosten $45.00
Lieferung in 2 bis 3 Werktagen
  • Target Alle EpCAM (EPCAM) Proteine anzeigen
    EpCAM (EPCAM)
    Protein-Typ
    Recombinant
    Proteineigenschaft
    AA 24-265
    Spezies
    • 19
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    Rhesusaffen
    Quelle
    • 12
    • 5
    • 5
    • 4
    • 4
    • 2
    • 1
    HEK-293 Cells
    Aufreinigungstag / Konjugat
    Dieses EpCAM Protein ist gelabelt mit His tag.
    Sequenz
    AA 24-265
    Produktmerkmale
    This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 28.2 kDa. The protein migrates as 28-40 kDa under reducing (R) condition (SDS-PAGE) due to different glycosylation.
    Reinheit
    >95 % as determined by SDS-PAGE.
    Sterilität
    0.22 μm filtered
    Endotoxin-Niveau
    Less than 1.0 EU per μg by the LAL method.
  • Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Buffer
    PBS, pH 7.4
    Handhabung
    Please avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    No activity loss was observed after storage at: In lyophilized state for 1 year (4 °C-8 °C), After reconstitution under sterile conditions for 1 month (4 °C-8 °C) or 3 months (-20 °C to -70 °C).
  • Target
    EpCAM (EPCAM)
    Andere Bezeichnung
    EpCAM (EPCAM Produkte)
    Synonyme
    DIAR5, EGP-2, EGP314, EGP40, ESA, HNPCC8, KS1/4, KSA, M4S1, MIC18, MK-1, TACSTD1, TROP1, ECS-1, ECS1, ESA1, M17S1, EGP, Ep-CAM, sb:cb6, tacstd, wu:fj17g02, zgc:110304, zgc:77119, tacstd1, MGC80540, EPCAM, egp, ksa, m4s1, mk-1, cd326, egp40, mic18, trop1, ep-cam, hegp-2, co17-1a, ga733-2, CD326, Egp314, EpCAM1, GA733-2, Ly74, Tacsd1, Tacstd1, gp40, epithelial cell adhesion molecule, flotillin 2, epithelial cell adhesion molecule S homeolog, EPCAM, FLOT2, epcam, epcam.S, Epcam
    Hintergrund
    EpCAM is also known as CO171A, EGP, EGP40,GA7332, KSA, M4S, MIC18, MK1, TROP1, hEGP2, and is a pan-epithelial differentiation antigen that is expressed on almost all carcinomas as 17-1A(mAb) antigen. Its constitutional function is being elucidated. It is intricately linked with the Cadherin-Catenin pathway and hence the fundamental WNT pathway responsible for intracellular signaling and polarity. The epithelial cell adhesion molecule (Ep-CAM) is known to express in most epithelial malignancies and was reported as a tumor marker or a candidate of molecular targeting therapy. Ep-CAM cross signaling with N-cadherin involves Pi3K, resulting in the abrogation of the cadherin adhesion complexes in epithelial cells was reported. And Epithelial cell adhesion molecule (Ep-CAM) recently received increased attention as a prognostic factor in breast cancer.
    Molekulargewicht
    28.2 kDa
    UniProt
    Q1WER1
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