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CD5 (CD5) (AA 25-372) protein (His tag) Protein

CD5 Spezies: Human Wirt: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE.
Produktnummer ABIN2180809
$275.00
Zzgl. Versandkosten $45.00
Lieferung in 2 bis 3 Werktagen
  • Target Alle CD5 Proteine anzeigen
    CD5
    Protein-Typ
    Recombinant
    Proteineigenschaft
    AA 25-372
    Spezies
    • 15
    • 4
    • 3
    • 1
    Human
    Quelle
    • 10
    • 4
    • 3
    • 3
    • 2
    • 1
    HEK-293 Cells
    Aufreinigungstag / Konjugat
    Dieses CD5 Protein ist gelabelt mit His tag.
    Sequenz
    AA 25-372
    Produktmerkmale
    This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 40.5 kDa. The protein migrates as 48-55 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
    Reinheit
    >95 % as determined by SDS-PAGE.
    Sterilität
    0.22 μm filtered
    Endotoxin-Niveau
    Less than 1.0 EU per μg by the LAL method.
  • Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Buffer
    PBS, pH 7.4
    Handhabung
    Please avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    No activity loss was observed after storage at: In lyophilized state for 1 year (4 °C), After reconstitution under sterile conditions for 3 months (-70 °C).
  • Target
    CD5
    Andere Bezeichnung
    CD5 (CD5 Produkte)
    Synonyme
    CD5, Ly-1, Ly-12, Ly-A, Lyt-1, LEU1, T1, CD5 molecule, CD5 antigen, CD5 molecule like, Cd5 molecule, CD5, Cd5, CD5L
    Hintergrund
    T-cell surface glycoprotein CD5 is also known as Lymphocyte antigen T1/Leu-1 and LEU1,which is phosphorylated on tyrosine residues by LYN,so CD5 can create binding sites for PTPN6/SHP-1.CD5 may act as a receptor in regulating T-cell proliferation. CD5 is expressed at various developmental and activation stages on human B cells.CD5 is a well established negative regulator of TCR and BCR signalling.CD5-positive cells may also prevent the emergence of autoimmunity by provision of cytokines such as IL-10. Development,selection and function of different B- and T-cell subsets or their preferential survival may be directly or indirectly dependent on different glycan structures associated with CD5 or CD5-like molecules.
    Molekulargewicht
    40.5 kDa
    NCBI Accession
    NP_055022
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