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Carbonic Anhydrase IX (CA9) (AA 38-414) protein (His tag) Protein

CA9 Spezies: Human Wirt: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE.
Produktnummer ABIN2180677
$385.00
Zzgl. Versandkosten $45.00
Lieferung in 2 bis 3 Werktagen
  • Target Alle CA9 Proteine anzeigen
    CA9
    Protein-Typ
    Recombinant
    Proteineigenschaft
    AA 38-414
    Spezies
    • 14
    • 4
    • 2
    • 1
    Human
    Quelle
    • 10
    • 6
    • 4
    • 1
    HEK-293 Cells
    Aufreinigungstag / Konjugat
    Dieses CA9 Protein ist gelabelt mit His tag.
    Sequenz
    AA 38-414
    Produktmerkmale
    This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 41.2 kDa. The protein migrates as 53-54 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
    Reinheit
    >90 % as determined by SDS-PAGE.
    Sterilität
    0.22 μm filtered
    Endotoxin-Niveau
    Less than 1.0 EU per μg by the LAL method.
  • Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Buffer
    20 mM MES, 100 mM NaCl, pH 6.5
    Handhabung
    Please avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    No activity loss was observed after storage at: In lyophilized state for 1 year (4 °C-8 °C), After reconstitution under sterile conditions for 1 month (4 °C-8 °C) or 3 months (-20 °C to -70 °C).
  • Target
    CA9
    Andere Bezeichnung
    Carbonic Anhydrase IX (CA9 Produkte)
    Synonyme
    CA9, CAIX, Ca9, MN/CA9, MN, carbonic anhydrase 9, CA9, CAH9, Car9
    Hintergrund
    Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes. CAs form a family of enzymes that catalyze the rapid interconversion of carbon dioxide and water to bicarbonate and protons (or vice versa), a reversible reaction that occurs rather slowly in the absence of a catalyst. One of the functions of the enzyme in animals is to interconvert carbon dioxide and bicarbonate to maintain acid-base balance in blood and other tissues, and to help transport carbon dioxide out of tissues. The active site of most carbonic anhydrases contains a zinc ion. There are at least five distinct CA families (α, β, γ, δ and ε). Carbonic anhydrase 9 (CA9 / CAIX) is also known as Membrane antigen MN (MN), Renal cell carcinoma-associated antigen G250, which belongs to the alpha-carbonic anhydrase family. CA9 / CAIX with an optimal activity at pH 6.49. Reversible hydration of carbon dioxide. CA IX participates in pH regulation. CA9 may be involved in the control of cell proliferation and transformation. CA-IX appears to be a novel specific biomarker for a cervical neoplasia.
    Molekulargewicht
    41.7 kDa
    NCBI Accession
    NP_001207
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