Telefon:
+1 877 302 8632
Fax:
+1 888 205 9894 (Toll-free)
E-Mail:
orders@antikoerper-online.de

Angiopoietin-Like 3 (ANGPTL3) (AA 17-220) protein (His tag) Protein

ANGPTL3 Spezies: Human Wirt: HEK-293 Cells Recombinant >95 % as determined by reduced SDS-PAGE.
Produktnummer ABIN2180588
$346.50
Zzgl. Versandkosten $45.00
Lieferung in 2 bis 3 Werktagen
  • Target Alle ANGPTL3 Proteine anzeigen
    ANGPTL3
    Protein-Typ
    Recombinant
    Proteineigenschaft
    AA 17-220
    Spezies
    • 14
    • 6
    • 2
    Human
    Quelle
    • 12
    • 4
    • 2
    • 1
    • 1
    • 1
    HEK-293 Cells
    Aufreinigungstag / Konjugat
    Dieses ANGPTL3 Protein ist gelabelt mit His tag.
    Sequenz
    AA 17-220
    Produktmerkmale
    This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 24.6 kDa. The protein migrates as 26-38 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
    Reinheit
    >95 % as determined by reduced SDS-PAGE.
    Sterilität
    0.22 μm filtered
    Endotoxin-Niveau
    Less than 1.0 EU per μg by the LAL method.
  • Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Buffer
    PBS, pH 7.4
    Handhabung
    Please avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    No activity loss was observed after storage at: In lyophilized state for 1 year (4 °C), After reconstitution under sterile conditions for 3 months (-70 °C).
  • Target
    ANGPTL3
    Andere Bezeichnung
    Angiopoietin-Like 3 (ANGPTL3 Produkte)
    Synonyme
    fb60e11, fb66h02, wu:fb60e11, wu:fb66h02, zgc:111943, ANGPTL3, LOC100230785, ANG-5, ANGPT5, ANL3, FHBL2, hypl, angiopoietin-like 3, angiopoietin like 3, angptl3, ANGPTL3, Angptl3
    Hintergrund
    Angiopoietin-like protein 3 (ANGPTL3) is also known as Angiopoietin-related protein 3, Angiopoietin-5 (ANGPT5 / ANG-5), is a member of the angiopoietin-like family of secreted factors. ANGPTL3 / ANGPT5 is predominantly expressed in the liver, and has the characteristic structure of angiopoietins, consisting of a signal peptide, N-terminal coiled-coil domain and the C-terminal fibrinogen (FBN)-like domain. The FBN-like domain in angiopoietin-like 3 protein was shown to bind alpha-5/beta-3 integrins, and this binding induced endothelial cell adhesion and migration. This protein may also play a role in the regulation of angiogenesis. Angptl3 also acts as dual inhibitor of lipoprotein lipase (LPL) and endothelial lipase (EL), and increases plasma triglyceride and HDL cholesterol in rodents. ANGPTL3 inhibit endothelial lipase to catalyze HDL-phospholipid and increase HDL-PL levels. Circulating PL-riched HDL particles have high cholesterol efflux abilities.
    Molekulargewicht
    24.6 kDa
    NCBI Accession
    NP_055310
Sie sind hier:
Kundenservice