Thyroperoxidase Protein (full length)

Produktnummer ABIN2132174

Dieses Recombinant Thyroperoxidase-Protein wird in Insect cells (Sf9) produziert.

Kurzübersicht für Thyroperoxidase Protein (full length) (ABIN2132174)

Target: Thyroperoxidase (TPO) (Thyroid Peroxidase (TPO))

Protein-Typ: Recombinant

Spezies: Human

Quelle: Insect cells (Sf9)

Applikation: Western Blotting (WB), ELISA

Reinheit: > 95 % pure

Produktdetails

Proteineigenschaft: full length

Produktmerkmale: Purified recombinant Human Thyroid Peroxidase protein
Expression System: Sf-9 insect cells

Aufreinigung: Proprietary chromatographic technique

Anwendungsinformationen

Applikationshinweise: Each Investigator should determine their own optimal working dilution for specific applications.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: 16 mM HEPES, pH 7.6, with 166 mM NaCl, 0.06 mM Kl and 20 % glycerol.

Handhabung: Avoid repeated freeze/thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 4 °C for short term storage. Aliquot and store at -20 °C for long term storage.

Antigendetails

Target: Thyroperoxidase (TPO) (Thyroid Peroxidase (TPO))

Andere Bezeichnung: Thyroid Peroxidase

Hintergrund: Thyroid Peroxidase (TPO) represents one of the main autoantigenic targets in autoimmune thyroid disease of humans. Its identity with the formerly so-called `microsomal antigen` has been shown several years ago. As an integral membrane glycoprotein it is restricted to the apical plasma membrane of the follicular epithelial cells and comprises two identical subunits of approx. 100 kDa molecular weight. The hemoprotein TPO plays a key role in the thyroid hormone biosynthesis by catalysing both the iodination of tyrosyl residues and the coupling of iodotyrosyl residues in thyroglobulin (TG) to form precursors of the thyroid hormones T4 and T3.
Alternative Names: TPX protein, MSA protein, TPO protein

Molekulargewicht: 101 kDa

Pathways: Thyroid Hormone Synthesis