CCL5 Protein
Kurzübersicht für CCL5 Protein (ABIN935753)
Target
Alle CCL5 Proteine anzeigenProtein-Typ
Biologische Aktivität
Spezies
Quelle
Reinheit
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Sequenz
- SPYGSDTTPC CFAYLSLALP RAHVKEYFYT SSKCSNLAVV FVTRRNRQVC ANPEKKWVQE YINYLEMS
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Produktmerkmale
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Purified recombinant Mouse RANTES protein
Expression System: E.coli
Bioactivity: Determined by its ability to chemoattract total human lymph °Cyte population and total Mouse T cell population using a concentration range of 1.0-10.0 ng/mL. -
Endotoxin-Niveau
- < 0.1 ng per μg (1 EU/μg) of RANTES.
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Applikationshinweise
- Each Investigator should determine their own optimal working dilution for specific applications.
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Kommentare
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Biological activity: Determined by its ability to chemoattract total human lymph DEG Cyte population and total Mouse T cell population using a concentration range of 1.0-10.0 ng/mL.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Reconstitute in water to a concentration of 0.1-1.0 mg/mL.
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Buffer
- Supplied lyophilized with no additives.
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Konservierungsmittel
- Without preservative
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Handhabung
- Avoid repeated freeze/thaw cycles.
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Lagerung
- 4 °C/-20 °C
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Informationen zur Lagerung
- Store at 4 °C until reconstitution. Following reconstitution aliquot and freeze at -20 °C for long term storage.
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- CCL5 (Chemokine (C-C Motif) Ligand 5 (CCL5))
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Andere Bezeichnung
- RANTES
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Hintergrund
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RANTES is a CC-chemokine that can signal through the CCR1, CCR3, CCR5 and US28 (cytomegalovirus receptor) receptors. It is a chemoattractant towards monocytes, memory T cells (CD4+/CD45RO), basophils, and eosinophils. RANTES also has the capability to inhibit certain strains of HIV-1, HIV-2 and simian immunodeficiency virus (SIV).
Alternative Names: Regulation upon Activation Normal T cell Express Sequence protein, SIS-delta protein, CCL5 protein -
Molekulargewicht
- 7.8 kDa
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Pathways
- Cellular Response to Molecule of Bacterial Origin, Regulation of G-Protein Coupled Receptor Protein Signaling, Smooth Muscle Cell Migration
Target
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