TMSB4X Protein

Produktnummer ABIN2018400

Dieses Recombinant TMSB4X-Protein wird in Escherichia coli (E. coli) exprimiert.

Kurzübersicht für TMSB4X Protein (ABIN2018400)

Target: TMSB4X (Thymosin beta-4 (TMSB4X))

Protein-Typ: Recombinant

Biologische Aktivität: Active

Spezies: Human

Quelle: Escherichia coli (E. coli)

Reinheit: > 97 % by SDS-PAGE and HPLC analyses.

Produktdetails

Sequenz: SDKPDMAEIE KFDKSKLKKT ETQEKNPLPS KETIEQEKQA GES

Produktmerkmale: Fully biologically active when compared to standard. The biological activity determined by its ability to produce a protective effect against hydrogen peroxide in primary lung fibroblasts is in a concentration range of 0.5 - 10 μg/mL.

Sterilität: 0.2 μm filtered

Endotoxin-Niveau: < 1 EU/μg of rHuTμ4 as determined by LAL method.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1 % BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at ≤ -20 °C. Further dilutions should be made in appropriate buffered solutions.

Buffer: Lyophilized from a 0.2 μm filtered concentrated solution in 20 mM PB, pH 7.4.

Handhabung: Avoid repeated freeze/thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: This lyophilized preparation is stable at 2-8 °C, but should be kept at -20 °C for long term storage, preferably desiccated. Upon reconstitution, the preparation is stable for up to one week at 2-8 °C. For maximal stability, apportion the reconstituted preparation into working aliquots and store at -20 °C to -70 °C.

Antigendetails

Target: TMSB4X (Thymosin beta-4 (TMSB4X))

Andere Bezeichnung: Thymosin beta 4

Hintergrund: Thymosin Beta 4 is a naturally occurring peptide. It is found in high concentrations in blood platelets, wound fluid and other tissues in the body. T beta4 is not a growth factor, rather, it is a major actin regulating peptide. The thymosin beta-4 peptide, if used after a heart attack, might reactivate cardiac progenitor cells to repair damaged heart tissue.
Synonyms: T beta 4 Human,

Molekulargewicht: 4.9 kDa, a single non-glycosylated polypeptide chain containing 43 amino acids.

Pathways: Regulation of Actin Filament Polymerization, Regulation of Muscle Cell Differentiation, Maintenance of Protein Location, Smooth Muscle Cell Migration