CCL20 Protein (AA 27-96)

Produktnummer ABIN2018255

Produktdetails

Target: CCL20 (Chemokine (C-C Motif) Ligand 20 (CCL20))

Protein-Typ: Recombinant

Biologische Aktivität: Active

Proteineigenschaft: AA 27-96

Spezies: Human

Quelle: CHO Cells

Produktmerkmale: The EC50 value of humanMIP-3 alpha/CCL20 on Ca2+ mobilization assay in CHO-K1/Ga15/hCCR6 cells (human Ga15 and human CCR6 stably expressed in CHO-K1 cells) is less than 200 ng/mL.

Reinheit: > 98 % as analyzed by SDS-PAGE.

Endotoxin-Niveau: < 0.2 EU/μg, determined by LAL method.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Reconstituted in ddH2O or PBS at 100 μg/mL.

Buffer: Lyophilized after extensive dialysis against PBS.

Lagerung: -80 °C

Informationen zur Lagerung: Lyophilized recombinant Human MIP-3 alpha/CCL20 remains stable up to 6 months at -80 °C from date of receipt. Upon reconstitution, Human MIP-3 alpha/CCL20 should be stable up to 1 week at 4 °C or up to 2 months at -20 °C.

Haltbarkeit: 6 months

Antigendetails

Target: CCL20 (Chemokine (C-C Motif) Ligand 20 (CCL20))

Andere Bezeichnung: MIP-3 alpha/ccl20 (CCL20 Produkte)

Hintergrund: Chemokine (C-C motif) ligand 20 (CCL20) also known as liver activation regulated chemokine (LARC) or Macrophage Inflammatory Protein-3 (MIP3 alpha) is a small cytokine belonging to the CC chemokine family. It is strongly chemotactic for lymphocytes and weakly attracts neutrophils. Additionally, it promotes the adhesion of memory CD4+ T cells and inhibits colony formation of bone marrow myeloid immature progenitors.Recombinant humanMIP-3 alpha/CCL20 produced in CHO cells is a polypeptide chain containing 70 amino acids. A fully biologically active molecule, rhMIP-3 alpha/CCL20 has a molecular mass of 8 kDa analyzed by reducing SDS-PAGE.
Synonyms: MIP-3 alpha/CCL20, Human

Molekulargewicht: 8 kDa, observed by reducing SDS-PAGE.

UniProt: P78556

Pathways: Phosphorylierungen bei SARS-CoV-2 Infektion