CCL20 Protein (AA 27-96)
Kurzübersicht für CCL20 Protein (AA 27-96) (ABIN2018253)
Target
Alle CCL20 Proteine anzeigenProtein-Typ
Biologische Aktivität
Spezies
Quelle
Reinheit
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Proteineigenschaft
- AA 27-96
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Produktmerkmale
- The EC50 value of humanMIP-3 alpha/CCL20 on Ca2+ mobilization assay in CHO-K1/Ga15/hCCR6 cells (human Ga15 and human CCR6 stably expressed in CHO-K1 cells) is less than 200 ng/mL.
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Endotoxin-Niveau
- < 0.2 EU/μg, determined by LAL method.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Reconstituted in ddH2O or PBS at 100 μg/mL.
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Buffer
- Lyophilized after extensive dialysis against PBS.
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Lagerung
- -80 °C
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Informationen zur Lagerung
- Lyophilized recombinant Human MIP-3 alpha/CCL20 remains stable up to 6 months at -80 °C from date of receipt. Upon reconstitution, Human MIP-3 alpha/CCL20 should be stable up to 1 week at 4 °C or up to 2 months at -20 °C.
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Haltbarkeit
- 6 months
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- CCL20 (Chemokine (C-C Motif) Ligand 20 (CCL20))
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Andere Bezeichnung
- MIP-3 alpha/ccl20
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Hintergrund
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Chemokine (C-C motif) ligand 20 (CCL20) also known as liver activation regulated chemokine (LARC) or Macrophage Inflammatory Protein-3 (MIP3 alpha) is a small cytokine belonging to the CC chemokine family. It is strongly chemotactic for lymphocytes and weakly attracts neutrophils. Additionally, it promotes the adhesion of memory CD4+ T cells and inhibits colony formation of bone marrow myeloid immature progenitors.Recombinant humanMIP-3 alpha/CCL20 produced in CHO cells is a polypeptide chain containing 70 amino acids. A fully biologically active molecule, rhMIP-3 alpha/CCL20 has a molecular mass of 8 kDa analyzed by reducing SDS-PAGE.
Synonyms: MIP-3 alpha/CCL20, Human -
Molekulargewicht
- 8 kDa, observed by reducing SDS-PAGE.
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UniProt
- P78556
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Pathways
- Phosphorylierungen bei SARS-CoV-2 Infektion
Target
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