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CCL20 Protein (AA 27-96)

Dieses Recombinant CCL20-Protein wird in CHO Cells exprimiert.
Produktnummer ABIN2018253

Kurzübersicht für CCL20 Protein (AA 27-96) (ABIN2018253)

Target

Alle CCL20 Proteine anzeigen
CCL20 (Chemokine (C-C Motif) Ligand 20 (CCL20))

Protein-Typ

Recombinant

Biologische Aktivität

Active

Spezies

  • 16
  • 8
  • 4
  • 4
  • 2
  • 2
  • 2
  • 1
Human

Quelle

  • 30
  • 4
  • 2
  • 1
  • 1
CHO Cells

Reinheit

> 98 % as analyzed by SDS-PAGE.
  • Proteineigenschaft

    AA 27-96

    Produktmerkmale

    The EC50 value of humanMIP-3 alpha/CCL20 on Ca2+ mobilization assay in CHO-K1/Ga15/hCCR6 cells (human Ga15 and human CCR6 stably expressed in CHO-K1 cells) is less than 200 ng/mL.

    Endotoxin-Niveau

    < 0.2 EU/μg, determined by LAL method.
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  • Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Rekonstitution

    Reconstituted in ddH2O or PBS at 100 μg/mL.

    Buffer

    Lyophilized after extensive dialysis against PBS.

    Lagerung

    -80 °C

    Informationen zur Lagerung

    Lyophilized recombinant Human MIP-3 alpha/CCL20 remains stable up to 6 months at -80 °C from date of receipt. Upon reconstitution, Human MIP-3 alpha/CCL20 should be stable up to 1 week at 4 °C or up to 2 months at -20 °C.

    Haltbarkeit

    6 months
  • Target

    CCL20 (Chemokine (C-C Motif) Ligand 20 (CCL20))

    Andere Bezeichnung

    MIP-3 alpha/ccl20

    Hintergrund

    Chemokine (C-C motif) ligand 20 (CCL20) also known as liver activation regulated chemokine (LARC) or Macrophage Inflammatory Protein-3 (MIP3 alpha) is a small cytokine belonging to the CC chemokine family. It is strongly chemotactic for lymphocytes and weakly attracts neutrophils. Additionally, it promotes the adhesion of memory CD4+ T cells and inhibits colony formation of bone marrow myeloid immature progenitors.Recombinant humanMIP-3 alpha/CCL20 produced in CHO cells is a polypeptide chain containing 70 amino acids. A fully biologically active molecule, rhMIP-3 alpha/CCL20 has a molecular mass of 8 kDa analyzed by reducing SDS-PAGE.
    Synonyms: MIP-3 alpha/CCL20, Human

    Molekulargewicht

    8 kDa, observed by reducing SDS-PAGE.

    UniProt

    P78556

    Pathways

    Phosphorylierungen bei SARS-CoV-2 Infektion
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