FGF18 Protein (AA 27-199)

Produktnummer ABIN2017816

Dieses Recombinant FGF18-Protein wird in Escherichia coli (E. coli) exprimiert.

Kurzübersicht für FGF18 Protein (AA 27-199) (ABIN2017816)

Target: FGF18 (Fibroblast Growth Factor 18 (FGF18))

Protein-Typ: Recombinant

Biologische Aktivität: Active

Spezies: Human

Quelle: Escherichia coli (E. coli)

Reinheit: > 95 % by SDS-PAGE and HPLC analyses.

Produktdetails

Proteineigenschaft: AA 27-199

Produktmerkmale: ED50 < 10 ng/mL, measured by a cell proliferation assay using 3T3 Cells, corresponding to a specific activity of > 1.0x 105 units/mg.
AA 27 -199, expressed with an N-terminal Met.

Endotoxin-Niveau: < 0.2 EU/μg, determined by LAL method.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Reconstituted in ddH2O at 100 μg/mL.

Buffer: Lyophilized after extensive dialysis against PBS.

Lagerung: -80 °C

Informationen zur Lagerung: Lyophilized recombinant human Fibroblast Growth Factor-18 (rhFGF-18) remains stable up to 6 months at -80 °C from date of receipt. Upon reconstitution, rhFGF-18 should be stable up to 2 weeks at 4 °C or up to 3 months at -20 °C.

Haltbarkeit: 6 months

Antigendetails

Target: FGF18 (Fibroblast Growth Factor 18 (FGF18))

Andere Bezeichnung: Fibroblast Growth Factor-18 (FGF-18)

Hintergrund: Fibroblast Growth Factor-18 (FGF-18) is a heparin-binding growth factor that is a member of the FGF family. FGF-18 signals through FGFR 1c, 2c, 3c, and 4. FGF-18 plays an important role in the regulation of cell proliferation, cell differentiation and cell migration. FGF-18 is required for normal ossification and bone development. It can also stimulate hepatic and intestinal proliferation.Recombinant human Fibroblast Growth Factor-18 (rhFGF-18) produced in E. coli is a single non-glycosylated polypeptide chain containing 174 amino acids. A fully biologically active molecule, rhFGF-18 has a molecular mass of 20.3 kDa analyzed by reducing SDS-PAGE.
Synonyms: Fibroblast Growth Factor-18, zFGF5, FGFI

Molekulargewicht: 20.3 kDa, observed by reducing SDS-PAGE.

UniProt: O76093

Pathways: Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung