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FGF18 Protein (AA 27-199)

Dieses Recombinant FGF18-Protein wird in Escherichia coli (E. coli) exprimiert.
Produktnummer ABIN2017817

Kurzübersicht für FGF18 Protein (AA 27-199) (ABIN2017817)

Target

Alle FGF18 Proteine anzeigen
FGF18 (Fibroblast Growth Factor 18 (FGF18))

Protein-Typ

Recombinant

Biologische Aktivität

Active

Spezies

  • 6
  • 4
  • 2
  • 1
Human

Quelle

  • 9
  • 2
  • 1
  • 1
Escherichia coli (E. coli)

Reinheit

> 95 % by SDS-PAGE and HPLC analyses.
  • Proteineigenschaft

    AA 27-199

    Produktmerkmale

    ED50 < 10 ng/mL, measured by a cell proliferation assay using 3T3 Cells, corresponding to a specific activity of > 1.0x 105 units/mg.
    AA 27 -199, expressed with an N-terminal Met.

    Endotoxin-Niveau

    < 0.2 EU/μg, determined by LAL method.
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  • Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Rekonstitution

    Reconstituted in ddH2O at 100 μg/mL.

    Buffer

    Lyophilized after extensive dialysis against PBS.

    Lagerung

    -80 °C

    Informationen zur Lagerung

    Lyophilized recombinant human Fibroblast Growth Factor-18 (rhFGF-18) remains stable up to 6 months at -80 °C from date of receipt. Upon reconstitution, rhFGF-18 should be stable up to 2 weeks at 4 °C or up to 3 months at -20 °C.

    Haltbarkeit

    6 months
  • Target

    FGF18 (Fibroblast Growth Factor 18 (FGF18))

    Andere Bezeichnung

    Fibroblast Growth Factor-18 (FGF-18)

    Hintergrund

    Fibroblast Growth Factor-18 (FGF-18) is a heparin-binding growth factor that is a member of the FGF family. FGF-18 signals through FGFR 1c, 2c, 3c, and 4. FGF-18 plays an important role in the regulation of cell proliferation, cell differentiation and cell migration. FGF-18 is required for normal ossification and bone development. It can also stimulate hepatic and intestinal proliferation.Recombinant human Fibroblast Growth Factor-18 (rhFGF-18) produced in E. coli is a single non-glycosylated polypeptide chain containing 174 amino acids. A fully biologically active molecule, rhFGF-18 has a molecular mass of 20.3 kDa analyzed by reducing SDS-PAGE.
    Synonyms: Fibroblast Growth Factor-18, zFGF5, FGFI

    Molekulargewicht

    20.3 kDa, observed by reducing SDS-PAGE.

    UniProt

    O76093

    Pathways

    Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung
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