ADIPOQ Protein (AA 19-244)
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- Target Alle ADIPOQ Proteine anzeigen
- ADIPOQ (Adiponectin (ADIPOQ))
- Protein-Typ
- Recombinant
- Biologische Aktivität
- Active
- Proteineigenschaft
- AA 19-244
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Spezies
- Human
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Quelle
- CHO Cells
- Produktmerkmale
- ED50 < 2 ng/mL, measured in a cell growth inhibition assay using M1 cells.
- Reinheit
- > 95 % as analyzed by SDS-PAGE and HPLC.
- Endotoxin-Niveau
- < 0.2 EU/μg, determined by LAL method.
- Top Product
- Discover our top product ADIPOQ Protein
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- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Rekonstitution
- Reconstituted in ddH2O or PBS at 100 μg/mL.
- Buffer
- Lyophilized after extensive dialysis against PBS.
- Lagerung
- -80 °C
- Informationen zur Lagerung
- Lyophilized recombinant Human Adiponectin remains stable up to 6 months at -80 °C from date of receipt. Upon reconstitution, Human Adiponectinshould be stable up to 1 week at 4 °C or up to 2 months at -20 °C.
- Haltbarkeit
- 6 months
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- Target
- ADIPOQ (Adiponectin (ADIPOQ))
- Andere Bezeichnung
- Adiponectin (ADIPOQ Produkte)
- Hintergrund
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Adiponectin is an important adipokine involved in the control of fat metabolism and insulin sensitivity. It is synthesized exclusively by adipocytes and secreted into plasma. It antagonizes THF-alpha by negatively regulating its expression. It also inhibits endothelial NF-kappa-B signaling through a cAMP-dependent pathway. Adiponectin can form low molecular weight complexes (LMW), middle molecular weight complexes (MMW) and higher molecular weight complexes (HMW). These bind to various growth factors, such as HBEGF, PDGFB and FGF2, and play a role in cell growth, angiogenesis and tissue remodeling.
Synonyms: Acrp-30, GBP-28, Apm-1 - Molekulargewicht
- 25-28 kDa, observed by reducing SDS-PAGE.
- UniProt
- Q15848
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