ADIPOQ Protein (AA 19-244)

Produktnummer ABIN2017662

Recombinant ADIPOQ-Protein exprimiert in CHO Cells.

Kurzübersicht für ADIPOQ Protein (AA 19-244) (ABIN2017662)

Target: ADIPOQ (Adiponectin (ADIPOQ))

Protein-Typ: Recombinant

Biologische Aktivität: Active

Spezies: Human

Quelle: CHO Cells

Reinheit: > 95 % as analyzed by SDS-PAGE and HPLC.

Produktdetails

Proteineigenschaft: AA 19-244

Produktmerkmale: ED50 < 2 ng/mL, measured in a cell growth inhibition assay using M1 cells.

Endotoxin-Niveau: < 0.2 EU/μg, determined by LAL method.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Reconstituted in ddH2O or PBS at 100 μg/mL.

Buffer: Lyophilized after extensive dialysis against PBS.

Lagerung: -80 °C

Informationen zur Lagerung: Lyophilized recombinant Human Adiponectin remains stable up to 6 months at -80 °C from date of receipt. Upon reconstitution, Human Adiponectinshould be stable up to 1 week at 4 °C or up to 2 months at -20 °C.

Haltbarkeit: 6 months

Antigendetails

Target: ADIPOQ (Adiponectin (ADIPOQ))

Andere Bezeichnung: Adiponectin

Hintergrund: Adiponectin is an important adipokine involved in the control of fat metabolism and insulin sensitivity. It is synthesized exclusively by adipocytes and secreted into plasma. It antagonizes THF-alpha by negatively regulating its expression. It also inhibits endothelial NF-kappa-B signaling through a cAMP-dependent pathway. Adiponectin can form low molecular weight complexes (LMW), middle molecular weight complexes (MMW) and higher molecular weight complexes (HMW). These bind to various growth factors, such as HBEGF, PDGFB and FGF2, and play a role in cell growth, angiogenesis and tissue remodeling.
Synonyms: Acrp-30, GBP-28, Apm-1

Molekulargewicht: 25-28 kDa, observed by reducing SDS-PAGE.

UniProt: Q15848