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FAM19A4 Protein (AA 35-140) (His tag)

Dieses Recombinant FAM19A4-Protein wird in Escherichia coli (E. coli) exprimiert.
Produktnummer ABIN1945371

Kurzübersicht für FAM19A4 Protein (AA 35-140) (His tag) (ABIN1945371)

Target

Alle FAM19A4 Proteine anzeigen
FAM19A4 (Family with Sequence Similarity 19 (Chemokine (C-C Motif)-Like), Member A4 (FAM19A4))

Protein-Typ

Recombinant

Spezies

  • 5
  • 1
Human

Quelle

  • 3
  • 1
  • 1
  • 1
Escherichia coli (E. coli)

Reinheit

> 95 % as determined by reducing SDS-PAGE.
  • Proteineigenschaft

    AA 35-140

    Aufreinigungstag / Konjugat

    Dieses FAM19A4 Protein ist gelabelt mit His tag.

    Verwendungszweck

    Recombinant Human Protein FAM19A4/FAM19A4 (N-6His)

    Sequenz

    MGSSHHHHHH SSGLVPRGSH MSSQHLRGHA GHHQIKQGTC EVVAVHRCCN KNRIEERSQT VKCSCFPGQV AGTTRAQPSC VEASIVIQKW WCHMNPCLEG EDCKVLPDYS GWSCSSGNKV KTTKVTR

    Produktmerkmale

    Recombinant Human Protein FAM19A4/FAM19A4 is produced with our E. coli expression system. The target protein is expressed with sequence (AA 35-140) of human TAFA4 fused with a His tag at the N-terminus.

    Sterilität

    0.2 μm filtered

    Endotoxin-Niveau

    Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
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  • Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Rekonstitution

    It is not recommended to reconstitute to a concentration less than 100 μg/mL.
    Dissolve the lyophilized protein in ddH2O.
    Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

    Buffer

    Lyophilized from a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl, pH 7.4.

    Handhabung

    Always centrifuge tubes before opening. Do not mix by vortex or pipetting.

    Lagerung

    4 °C/-20 °C/-80 °C

    Informationen zur Lagerung

    Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
    Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
    Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • Target

    FAM19A4 (Family with Sequence Similarity 19 (Chemokine (C-C Motif)-Like), Member A4 (FAM19A4))

    Andere Bezeichnung

    Protein FAM19A4/FAM19A4

    Hintergrund

    FAM19A4 is a secreted, 12 kDa member of the FAM19/TAFA family of chemokine-like proteins. Like other members of the FAM19/TAFA family, with the exception of TAFA5, mature FAM19A4 contains 10 regularly spaced cysteine residues. The FAM19A4 proteins are predominantly expressed in specific regions of the brain and the biological functions of FAM19A4 family members remain to be determined, but there are a few tentative hypotheses. First, FAM19A4 may modulate immune responses in the CNS by functioning as brain specific chemokines, and may act with other chemokines to optimize the recruitment and activity of immune cells in the CNS. Second, FAM19A4 may represent a novel class of neurokines that act as regulators of immune nervous cells. And third, FAM19A4 may control axonal sprouting following brain injury.

    Molekulargewicht

    14.1 kDa

    UniProt

    Q96LR4
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