MMP12 Protein (AA 106-267, Catalytic Domain)
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- Target Alle MMP12 Proteine anzeigen
- MMP12 (Matrix Metallopeptidase 12 (Macrophage Elastase) (MMP12))
- Protein-Typ
- Recombinant
- Proteineigenschaft
- AA 106-267, Catalytic Domain
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Spezies
- Human
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Quelle
- Escherichia coli (E. coli)
- Produktmerkmale
- The sequence corresponding to the catalytic domain (aa 106-267) of Human MMP-12 was expressed in E. Coli.
- Aufreinigung
- Purified from bacterial lysate and refolded using proprietary technique.
- Top Product
- Discover our top product MMP12 Protein
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- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Lagerung
- -80 °C
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- Target
- MMP12 (Matrix Metallopeptidase 12 (Macrophage Elastase) (MMP12))
- Andere Bezeichnung
- MMP-12 (MMP12 Produkte)
- Synonyme
- MMP12 Protein, AV378681 Protein, Mmel Protein, Mme Protein, HME Protein, ME Protein, MME Protein, MMP-12 Protein, matrix metallopeptidase 12 Protein, MMP12 Protein, Mmp12 Protein
- Hintergrund
- Matrix metalloproteinases (MMPs) belong to a family of secreted or membrane-associated zinc endopeptidases capable of digesting extracellular matrix components. MMP-12 (macrophage elastase) is involved in smoke-induced emphysema, tumor and other diseases. MMP-12 is secreted as a 54 kDa zymogen and becomes the mature 54 kDa active form after proteolytic cleavage. MMP-12 has a broad range of substrates, including alpha-1 proteinase inhibitor, alpha-2 antiplasmin, plasminogen activator inhibitor-2, collagen IV, laminin, fibronectin, elastin, but not interstitial collagens.
- Molekulargewicht
- 18 kDa
- NCBI Accession
- NP_002417
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