SNCA Protein (AA 1-140) (HiLyte Fluor 488)
Kurzübersicht für SNCA Protein (AA 1-140) (HiLyte Fluor 488) (ABIN1882766)
Target
Alle SNCA Proteine anzeigenProtein-Typ
Spezies
Quelle
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Proteineigenschaft
- AA 1-140
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Aufreinigungstag / Konjugat
- Dieses SNCA Protein ist gelabelt mit HiLyte Fluor 488.
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Produktmerkmale
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The recombinant human alpha-synuclein (1-140) was expressed and purified from E. coli and conjugated with the fluorescence dye HiLyte FluorTM 488.
Green fluorescence.
Excitation/Emission wavelengths= 503 nm/525 nm -
Aufreinigung
- Purified from E. Coli.
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Synuclein, alpha (SNCA) (A53T) (Active) protein
SNCA Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant SDS, WB, in vitro, in vivo Active
Synuclein, alpha (SNCA) (full length) (Active) proteinSNCA Spezies: Maus Wirt: Escherichia coli (E. coli) Recombinant SDS, WB, in vitro, in vivo Active
Synuclein, alpha (SNCA) (full length) (Active) proteinSNCA Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant >95% pure using SDS-PAGE analysis. SDS, WB, in vitro, in vivo Active
Synuclein, alpha (SNCA) (AA 1-140) protein (His tag)custom-made SNCA Spezies: Human Wirt: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Synuclein, alpha (SNCA) (AA 1-140) protein (His tag)custom-made SNCA Spezies: Maus Wirt: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Synuclein, alpha (SNCA) proteinSNCA Spezies: Maus Wirt: Escherichia coli (E. coli) Recombinant > 95 % as determined by SDS-PAGE
Synuclein, alpha (SNCA) (AA 1-140) protein (His tag)SNCA Spezies: Ratte Wirt: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Synuclein, alpha (SNCA) (active) proteinSNCA Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant > 95 % pure SDS
Synuclein, alpha (SNCA) (AA 31-140) protein (GST tag)SNCA Spezies: Human Wirt: Wheat germ Recombinant WB, ELISA, AP, AA
Synuclein, alpha (SNCA) (AA 1-140) protein (GST tag)SNCA Spezies: Human Wirt: Wheat germ Recombinant WB, ELISA, AP, AA
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Handhabung
- Protect from light!
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Lagerung
- -80 °C
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- SNCA (Synuclein, alpha (SNCA))
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Andere Bezeichnung
- alpha-Synuclein
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Hintergrund
- Parkinson's disease (PD) is predominantly a movement disorder resulting from degeneration of dopaminergic neurons in the substantia nigra. The cause of the disease is unknown, but substantial evidence suggests that the aggregation of alpha-synuclein is a critical step in the etiology of PD. alpha-Synuclein is an abundant protein of 140 residues that is present in high concentration at presynaptic terminals and is found in both soluble and membrane-associated fractions of the brain. Several possible functions have been suggested, among which are vesicle release and trafficking. In vitro incubation in the presence of salt (i.e. 0.1 M NaCl) with agitation causes alpha-synuclein to form fibrils.
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NCBI Accession
- NP_000336
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Pathways
- Synaptic Membrane, Regulation of G-Protein Coupled Receptor Protein Signaling, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process, Platelet-derived growth Factor Receptor Signaling, Negative Regulation of Transporter Activity, Regulation of long-term Neuronal Synaptic Plasticity
Target
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