SENP2 Protein (AA 363-589)
Kurzübersicht für SENP2 Protein (AA 363-589) (ABIN1880578)
Target
Alle SENP2 Proteine anzeigenProtein-Typ
Spezies
Quelle
Reinheit
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Proteineigenschaft
- AA 363-589
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Verwendungszweck
- Recombinant Human Sentrin-Specific Protease 2/SENP2
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Sequenz
- DDLLELTEDM EKEISNALGH GPQDEILSSA FKLRITRGDI QTLKNYHWLN DEVINFYMNL LVERNKKQGY PALHVFSTFF YPKLKSGGYQ AVKRWTKGVN LFEQEIILVP IHRKVHWSLV VIDLRKKCLK YLDSMGQKGH RICEILLQYL QDESKTKRNS DLNLLEWTHH SMKPHEIPQQ LNGSDCGMFT CKYADYISRD KPITFTQHQM PLFRKKMVWE ILHQQLL
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Produktmerkmale
- Recombinant Human Sentrin-specific protease 2 is produced by our E.coli expression system and the target gene encoding Asp363-Leu589 is expressed.
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Sterilität
- 0.2 μm filtered
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Endotoxin-Niveau
- Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Rekonstitution
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It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles. -
Buffer
- Supplied as a 0.2 um filtered solution of 50 mM HEPES, 5 % Glycerol, pH 7.4.
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Handhabung
- minimize freeze-thaw cycles
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at < -20°C, stable for 6 months after receipt. Please minimize freeze-thaw cycles.
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Haltbarkeit
- 6 months
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- SENP2 (SUMO1/sentrin/SMT3 Specific Peptidase 2 (SENP2))
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Andere Bezeichnung
- SENP2
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Sub Type
- Fusionprotein
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Hintergrund
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Alternative Names: Sentrin-specific protease 2, Axam2, SMT3-specific isopeptidase 2, Sentrin/SUMO-specific protease SENP2, KIAA1331, SENP2.SENP2 is an enzyme that belongs to the peptidase C48 family. SENP2 is a protease that catalyzes two essential functions in the SUMO pathway: processing of full-length SUMO1, SUMO2 and SUMO3 to their mature forms and deconjugation of SUMO1, SUMO2 and SUMO3 from targeted proteins. SUMO1 is a small ubiquitin-like protein that can be covalently conjugated to other proteins. It has been implicated as a down-regulator of CTNNB1 levels and may therefore be a modulator of the Wnt pathway.
Alternative Names: Sentrin-specific protease 2, Axam2, SMT3-specific isopeptidase 2, Sentrin/SUMO-specific protease SENP2, KIAA1331, SENP2. -
Molekulargewicht
- 26.8 kDa
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UniProt
- Q9HC62
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Pathways
- Chromatin Binding
Target
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