PGC Pepsinogen II (Active) Protein

Produktnummer ABIN1880433

Dieses Recombinant PGC Pepsinogen II-Protein wird in Escherichia coli (E. coli) exprimiert.

Kurzübersicht für PGC Pepsinogen II (Active) Protein (ABIN1880433)

Target: PGC Pepsinogen II

Protein-Typ: Recombinant

Biologische Aktivität: Active

Spezies: Human

Quelle: Escherichia coli (E. coli)

Applikation: ELISA, SDS-PAGE (SDS)

Reinheit: >95 % by SDS-PAGE

Produktdetails

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Tris-HCl( pH 7.4±0.2) with 0.2 % Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Shipat 4°C. Upon receipt, aliquot and store at -20°C or -80°C for long term. Avoid repeated freeze and thaw cycles.

Antigendetails

Target: PGC Pepsinogen II

Hintergrund:

Synonyms: Gastricsin, Pepsinogen C, PGC

Description: Recombinant full length human PG II protein with molecular weight 42 kDa.

Background: Pepsin is one of the main proteolytic enzymes secreted by the gastric mucosa. It consists of a single polypeptide chain and arises from its precursor, pepsinogen, by removal of a 41-amino acid segment from the amino end. There are 2 related pepsinogen systems in man: PGA, formerly PG I, precursor of pepsin A, and PGC, formerly PG II, precursor of pepsin C. In human gastric mucosa, 2 immunologically distinct classes of pepsinogen are synthesized. PG1 is restricted to the corpus, while PG2 is found throughout the stomach as well as in the proximal duodenum. PG1 is found in serum and urine in a ratio of about 1 to 10. PG2 is present in serum and seminal fluid but only trace amounts are found in urine. Serum PG1 and PG2 apparently originate from the stomach in the main, because the levels are very low after gastrectomy. PG2 in seminal fluid probably originates from the prostate.

Molekulargewicht: 42 kDa