Myoglobin Protein (MB)
Kurzübersicht für Myoglobin Protein (MB) (ABIN1880424)
Target
Alle Myoglobin (MB) Proteine anzeigenProtein-Typ
Biologische Aktivität
Spezies
Quelle
Applikation
Reinheit
-
-
Möchten Sie weitere Optionen für dieses Protein ?
!Entdecken Sie unsere vordefinierten maßgeschneiderten Proteine und Proteinservices!Ihr Projekt erfordert weitere Anpassungen? Kontaktieren Sie uns und entdecken Sie unsere maßgeschneiderten Proteinlösungen
-
Myoglobin (MB) (AA 2-100) protein (GST tag)
MB Spezies: Human Wirt: Wheat germ Recombinant ELISA, WB, AA, AP
Myoglobin (MB) (AA 2-154) protein (His tag)MB Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant Greater than 90 % as determined by SDS-PAGE. ELISA, WB
Myoglobin (MB) (AA 2-154) protein (His-IF2DI Tag)MB Spezies: Maus Wirt: Escherichia coli (E. coli) Recombinant Greater than 90 % as determined by SDS-PAGE. ELISA, WB
Myoglobin (MB) (AA 1-154) protein (His tag)MB Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant > 90 % SDS
-
-
Applikationshinweise
- Optimal working dilution should be determined by the investigator.
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Format
- Liquid
-
Buffer
- 50 mM Tris-HCl ( pH 8.0), 300 mM NaCl with 0.1 % SKL.
-
Lagerung
- 4 °C
-
Informationen zur Lagerung
- Ship at 4°C. Upon receipt, aliquot and store at 2-8°C for long term. Avoid repeated freeze and thaw cycles.
-
-
- Myoglobin (MB)
-
Andere Bezeichnung
- Myoglobin
-
Hintergrund
-
Synonyms: Myoglobin, MB, PVALB
Description: Recombinant full length human Myoglobin protein with molecular weight 17.8 kDa.
Background: Myoglobin, MB is an iron- and oxygen-binding protein found in the muscle tissue of vertebrates in general and in almost all mammals. It is a cytoplasmic hemoprotein, expressed solely in cardiac myocytes and oxidative skeletal muscle fibers, that reversibly binds O2 by its heme residue, a porphyrin ring:iron ion complex. MB is a single-chain globular protein of 153 or 154 amino acids, containing a heme prosthetic group in the center around which the remaining apoprotein folds. Myoglobin is released from damaged muscle tissue (rhabdomyolysis), which has very high concentrations of myoglobin. The released myoglobin is filtered by the kidneys but is toxic to the renal tubular epithelium and so may cause acute renal failure. It is a sensitive marker for muscle injury, making it a potential marker for heart attack in patients with chest pain. However, elevated myoglobin has low specificity for acute myocardial infarction (AMI) and thus CK-MB, cTnT, ECG, and clinical signs should be taken into account to make the diagnosis.
-
Molekulargewicht
- 17.8 kDa
-
Pathways
- Brown Fat Cell Differentiation
Target
-
