Epididymis Protein 4 (HE-4) (Active) Protein

Produktnummer ABIN1880368

Recombinant Epididymis Protein 4 (HE-4)-Protein exprimiert in Escherichia coli (E. coli).

Kurzübersicht für Epididymis Protein 4 (HE-4) (Active) Protein (ABIN1880368)

Target: Epididymis Protein 4 (HE-4)

Protein-Typ: Recombinant

Biologische Aktivität: Active

Spezies: Human

Quelle: Escherichia coli (E. coli)

Applikation: ELISA, SDS-PAGE (SDS)

Reinheit: >95 % by SDS-PAGE

Produktdetails

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Tris-HCL ( pH 7.4±0.2) with 0.2 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Shipat 4°C. Upon receipt, aliquot and store at -20°C or -80°C for long term. Avoid repeated freeze and thaw cycles.

Antigendetails

Target: Epididymis Protein 4 (HE-4)

Andere Bezeichnung: Epididymis Protein 4

Hintergrund:

Synonyms: Human epididymis protein 4, HE4, WAP four-disulfide core domain protein 2, WFDC2

Description: Recombinant full length human HE4 protein with molecular weight 14 kDa.

Background: WAP four-disulfide core domain protein 2,also known as Human Epididymis Protein 4 (HE4) is a protein that in humans is encoded by the WFDC2 gene. This gene is amplified in ovarian carcinomas, whereas its expression in normal tissues, including ovary, is low. Although the function of the HE4 protein is unknown,it is a member of a family of stable 4-disulfide core proteins that are secreted at high levels.HE4 is a secreted glycoprotein that is overexpressed by serous and endometrioid EOCs(epithelial ovarian carcinomas). Its expression in cortical inclusion cysts suggests that formation of Mullerian epithelium is a prerequisite step in the development of some types ofEOCs.

Molekulargewicht: 14 kDa