ACAT2 Protein (AA 1-397) (His-TRX)

Produktnummer ABIN1692521

Dieses Recombinant ACAT2-Protein wird in Escherichia coli (E. coli) exprimiert.

Kurzübersicht für ACAT2 Protein (AA 1-397) (His-TRX) (ABIN1692521)

Target: ACAT2 (Acetyl-CoA Acetyltransferase 2 (ACAT2))

Protein-Typ: Recombinant

Spezies: Human

Quelle: Escherichia coli (E. coli)

Reinheit: > 95 % as determined by reducing SDS-PAGE.

Produktdetails

Proteineigenschaft: AA 1-397

Aufreinigungstag / Konjugat: Dieses ACAT2 Protein ist gelabelt mit His-TRX.

Verwendungszweck: Recombinant Human Sterol O-Acyltransferase 2/SOAT2/ACAT2 (N-Trx, 6His)

Sequenz: MSDKIIHLTD DSFDTDVLKA DGAILVDFWA EWCGPCKMIA PILDEIADEY QGKLTVAKLN IDQNPGTAPK YGIRGIPTLL LFKNGEVAAT KVGALSKGQL KEFLDANLAG SGSGHMHHHH HHSSGLVPRG SGMKETAAAK FERQHMDSPD LGTDDDDKAM ADIGSMNAGS DPVVIVSAAR TIIGSFNGAL AAVPVQDLGS TVIKEVLKRA TVAPEDVSEV IFGHVLAAGC GQNPVRQASV GAGIPYSVPA WSCQMICGSG LKAVCLAVQS IGIGDSSIVV AGGMENMSKA PHLAYLRTGV KIGEMPLTDS ILCDGLTDAF HNCHMGITAE NVAKKWQVSR EDQDKVAVLS QNRTENAQKA GHFDKEIVPV LVSTRRGLIE VKTDEFPRHG SNIEAMSKLK PYFLTDGTGT VTPANASGIN DGAAAVVLMK KSEADKRGLT PLARIVSWSQ VGVEPSIMGI GPIPAIKQAV TKAGWSLEDV DIFEINEAFA AVSAAIVKEL GLNPEKVNIE GGAIALGHPL GASGCRILVT LLHTLERMGR SRGVAALCIG GGMGIAMCVQ RE

Produktmerkmale: Recombinant Human Sterol O-acyltransferase 2 is produced by our E.coli expression system and the target gene encoding Met1-Glu397 is expressed with a Trx, 6His tag at the N-terminus.

Sterilität: 0.2 μm filtered

Endotoxin-Niveau: Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Rekonstitution: It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Buffer: Supplied as a 0.2 um filtered solution of 20 mM Tris-HCl,100 mM NaCl,1 mM DTT,10 % Glycerol, pH 8.0.

Konservierungsmittel: Dithiothreitol (DTT)

Vorsichtsmaßnahmen: This product contains Dithiothreitol (DTT): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: minimize freeze-thaw cycles

Lagerung: -20 °C

Informationen zur Lagerung: Store at < -20°C, stable for 6 months after receipt. Please minimize freeze-thaw cycles.

Haltbarkeit: 6 months

Antigendetails

Target: ACAT2 (Acetyl-CoA Acetyltransferase 2 (ACAT2))

Andere Bezeichnung: ACAT2

Hintergrund: Alternative Names: Acetyl-CoA acetyltransferase cytosolic, Acetyl-CoA transferase-like protein, Cytosolic acetoacetyl-CoA thiolase, ACTL, ACAT2ACAT2 is a cytoplasmic enzyme which belongs to the thiolase family. ACAT2 takes part in lipid metabolism, lipoprotein assembly, catalyzing cholesterol esterification in mammalian cells. It is responsible for the synthesis of cholesteryl esters which are part of lipoproteins containing apoB. ACAT2 deficiency contributes to severe mental retardation and hypotonus.
Alternative Names: Acetyl-CoA acetyltransferase cytosolic, Acetyl-CoA transferase-like protein, Cytosolic acetoacetyl-CoA thiolase, ACTL, ACAT2

Molekulargewicht: 59.1 kDa

UniProt: O75908