Endoglin Protein (ENG) (AA 26-176) (His-TRX)
Kurzübersicht für Endoglin Protein (ENG) (AA 26-176) (His-TRX) (ABIN1692461)
Target
Alle Endoglin (ENG) Proteine anzeigenProtein-Typ
Spezies
Quelle
Reinheit
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Proteineigenschaft
- AA 26-176
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Aufreinigungstag / Konjugat
- Dieses Endoglin Protein ist gelabelt mit His-TRX.
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Verwendungszweck
- Recombinant Human Endoglin/CD105 (N-Trx, 6His)
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Sequenz
- MSDKIIHLTD DSFDTDVLKA DGAILVDFWA EWCGPCKMIA PILDEIADEY QGKLTVAKLN IDQNPGTAPK YGIRGIPTLL LFKNGEVAAT KVGALSKGQL KEFLDANLAG SGSGHMHHHH HHSSGLVPRG SGMKETAAAK FERQHMDSPD LGTDDDDKAM ETVHCDLQPV GPERDEVTYT TSQVSKGCVA QAPNAILEVH VLFLEFPTGP SQLELTLQAS KQNGTWPREV LLVLSVNSSV FLHLQALGIP LHLAYNSSLV TFQEPPGVNT TELPSFPKTQ ILEWAAERGP ITSAAELNDP QSILLRLGQA Q
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Produktmerkmale
- Recombinant Human Endoglin is produced by our E.coli expression system and the target gene encoding Glu26-Gln176 is expressed with a Trx, 6His tag at the N-terminus.
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Sterilität
- 0.2 μm filtered
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Endotoxin-Niveau
- Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
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Endoglin (ENG) (AA 26-586) (Active) protein (His-Avi Tag)
ENG Spezies: Human Wirt: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 90 % as determined by HPLC Active
Endoglin (ENG) (AA 1-658) protein (GST tag)ENG Spezies: Human Wirt: Wheat germ Recombinant WB, ELISA, AA, AP
Endoglin (ENG) (AA 27-658) protein (GST tag)ENG Spezies: Human Wirt: Wheat germ Recombinant WB, ELISA, AA, AP
Endoglin (ENG) (AA 394-581) protein (His-IF2DI Tag)ENG Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA
Endoglin (ENG) (AA 27-581) (Active) protein (His tag)ENG Spezies: Maus Wirt: Baculovirus infected Insect Cells Recombinant > 95 % SDS, AcA Active
Endoglin (ENG) (AA 26-586) protein (His tag)ENG Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant > 85 % SDS
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Rekonstitution
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It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles. -
Buffer
- Supplied as a 0.2 um filtered solution of 20 mM PB, 150 mM NaCl, pH 7.4.
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Handhabung
- minimize freeze-thaw cycles
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at < -20°C, stable for 6 months after receipt. Please minimize freeze-thaw cycles.
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Haltbarkeit
- 6 months
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- Endoglin (ENG)
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Andere Bezeichnung
- Endoglin
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Sub Type
- Fusionprotein
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Hintergrund
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Alternative Names: Endoglin, END, CD105, ENGEndoglin is a single-pass type I membrane protein which restricted to endothelial cells in all tissues except bone marrow. Endoglin as major glycoprotein of vascular endothelium, it has been found on endothelial cells, activated macrophages, fibroblasts, and smooth muscle cells. Furthermore, Homodimer forms a heteromeric complex with the signaling receptors for transforming growth factor-beta: TGFBR1 and/or TGFBR2. It may have an important role in the binding of endothelial cells to integrins and/or other RGD receptors. Defects in ENG are the cause of hereditary hemorrhagic telangiectasia type 1 (HHT1), which is an autosomal dominant multisystemic vascular dysplasia, characterized by recurrent epistaxis, muco-cutaneous telangiectases, gastro-intestinal hemorrhage, and pulmonary (PAVM), cerebral (CAVM) and hepatic arteriovenous malformations.
Alternative Names: Endoglin, END, CD105, ENG -
Molekulargewicht
- 33.6 kDa
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UniProt
- P17813
Target
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