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Ccl21a Protein (AA 24-133)

Recombinant Ccl21a-Protein exprimiert in Escherichia coli (E. coli).
Produktnummer ABIN1692325

Kurzübersicht für Ccl21a Protein (AA 24-133) (ABIN1692325)

Target

Alle Ccl21a (CCL21A) Proteine anzeigen
Ccl21a (CCL21A) (Chemokine (C-C Motif) Ligand 21A (Serine) (CCL21A))

Protein-Typ

Recombinant

Spezies

Maus

Quelle

  • 6
Escherichia coli (E. coli)

Reinheit

> 95 % as determined by reducing SDS-PAGE.
  • Proteineigenschaft

    AA 24-133

    Verwendungszweck

    Recombinant Mouse C-C Motif Chemokine 21a/CCL21a//6Ckine

    Sequenz

    SDGGGQDCCL KYSQKKIPYS IVRGYRKQEP SLGCPIPAIL FSPRKHSKPE LCANPEEGWV QNLMRRLDQP PAPGKQSPGC RKNRGTSKSG KKGKGSKGCK RTEQTQPSRG

    Produktmerkmale

    Recombinant Mouse C-C Motif Chemokine 21a/CCL21a//6Ckine

    Sterilität

    0.2 μm filtered

    Endotoxin-Niveau

    Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
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  • Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Rekonstitution

    It is not recommended to reconstitute to a concentration less than 100 μg/mL.
    Dissolve the lyophilized protein in ddH2O.
    Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

    Buffer

    Lyophilized from a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl, pH 7.4.

    Handhabung

    Always centrifuge tubes before opening. Do not mix by vortex or pipetting.

    Lagerung

    4 °C/-20 °C/-80 °C

    Informationen zur Lagerung

    Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
    Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
    Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • Target

    Ccl21a (CCL21A) (Chemokine (C-C Motif) Ligand 21A (Serine) (CCL21A))

    Andere Bezeichnung

    C-C Motif Chemokine 21a/CCL21a

    Hintergrund

    Recombinant Mouse C-C Motif Chemokine 21a/CCL21a is produced with our E. coli expression system. The target protein is expressed with sequence (Ser24-Gly133) of Mouse CCL21a.
    C-C Motif Chemokine 21a (CCL21a) is a small secreted cytokine that belongs to the intercrine β (CC chemokine) family. Mouse CCL21 cDNA encodes a 133 AA residue protein with a 23 residue signal peptide that is cleaved to generate the 110 residue mature protein. Mouse CCL21 has three forms while CCL21a has Ser-65. CCL21 elicits its effects by binding to a cell surface chemokine receptor known as CCR7 and CXCR3. Mouse CCL21 inhibits hemopoiesis and stimulates chemotaxis. It has chemotactic function in vitro for thymocytes and activated T-cells, but not for B-cells, macrophages, or neutrophils. Mouse CCL21 shows preferential activity towards naive T-cells and may play a role in mediating homing of lymphocytes to secondary lymphoid organs.

    Molekulargewicht

    12 kDa

    UniProt

    P84444
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