Ccl21a Protein (AA 24-133)
Kurzübersicht für Ccl21a Protein (AA 24-133) (ABIN1692325)
Target
Alle Ccl21a (CCL21A) Proteine anzeigenProtein-Typ
Spezies
Quelle
Reinheit
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Proteineigenschaft
- AA 24-133
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Verwendungszweck
- Recombinant Mouse C-C Motif Chemokine 21a/CCL21a//6Ckine
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Sequenz
- SDGGGQDCCL KYSQKKIPYS IVRGYRKQEP SLGCPIPAIL FSPRKHSKPE LCANPEEGWV QNLMRRLDQP PAPGKQSPGC RKNRGTSKSG KKGKGSKGCK RTEQTQPSRG
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Produktmerkmale
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Recombinant Mouse C-C Motif Chemokine 21a/CCL21a//6Ckine
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Sterilität
- 0.2 μm filtered
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Endotoxin-Niveau
- Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
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It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles. -
Buffer
- Lyophilized from a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl, pH 7.4.
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Handhabung
- Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
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Lagerung
- 4 °C/-20 °C/-80 °C
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Informationen zur Lagerung
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Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- Ccl21a (CCL21A) (Chemokine (C-C Motif) Ligand 21A (Serine) (CCL21A))
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Andere Bezeichnung
- C-C Motif Chemokine 21a/CCL21a
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Hintergrund
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Recombinant Mouse C-C Motif Chemokine 21a/CCL21a is produced with our E. coli expression system. The target protein is expressed with sequence (Ser24-Gly133) of Mouse CCL21a.
C-C Motif Chemokine 21a (CCL21a) is a small secreted cytokine that belongs to the intercrine β (CC chemokine) family. Mouse CCL21 cDNA encodes a 133 AA residue protein with a 23 residue signal peptide that is cleaved to generate the 110 residue mature protein. Mouse CCL21 has three forms while CCL21a has Ser-65. CCL21 elicits its effects by binding to a cell surface chemokine receptor known as CCR7 and CXCR3. Mouse CCL21 inhibits hemopoiesis and stimulates chemotaxis. It has chemotactic function in vitro for thymocytes and activated T-cells, but not for B-cells, macrophages, or neutrophils. Mouse CCL21 shows preferential activity towards naive T-cells and may play a role in mediating homing of lymphocytes to secondary lymphoid organs. -
Molekulargewicht
- 12 kDa
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UniProt
- P84444
Target
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