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TREML1 Protein (Triggering Receptor Expressed On Myeloid Cells-Like 1) (AA 16-162) (Fc Tag)

TREML1 Spezies: Human Wirt: Human Cells Recombinant > 95 % as determined by reducing SDS-PAGE.
Produktnummer ABIN1691510
$313.50
Zzgl. Versandkosten $45.00
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  • Target Alle TREML1 Proteine anzeigen
    TREML1 (Triggering Receptor Expressed On Myeloid Cells-Like 1 (TREML1))
    Protein-Typ
    Recombinant
    Proteineigenschaft
    AA 16-162
    Spezies
    • 6
    • 4
    Human
    Quelle
    • 5
    • 3
    • 1
    • 1
    Human Cells
    Aufreinigungstag / Konjugat
    Dieses TREML1 Protein ist gelabelt mit Fc Tag.
    Verwendungszweck
    Recombinant Human TREML1/TLT-1 (C-Fc)
    Sequenz
    QGIVGSLPEV LQAPVGSSIL VQCHYRLQDV KAQKVWCRFL PEGCQPLVSS AVDRRAPAGR RTFLTDLGGG LLQVEMVTLQ EEDAGEYGCM VDGARGPQIL HRVSLNILPP EEEEETHKIG SLAENAFSDP AGSANPLEPS QDEKSIPVDD IEGRMDEPKS CDKTHTCPPC PAPELLGGPS VFLFPPKPKD TLMISRTPEV TCVVVDVSHE DPEVKFNWYV DGVEVHNAKT KPREEQYNST YRVVSVLTVL HQDWLNGKEY KCKVSNKALP APIEKTISKA KGQPREPQVY TLPPSREEMT KNQVSLTCLV KGFYPSDIAV EWESNGQPEN NYKTTPPVLD SDGSFFLYSK LTVDKSRWQQ GNVFSCSVMH EALHNHYTQK SLSLSPGK
    Produktmerkmale
    Recombinant Human Trem-like transcript 1 protein/TREML1/TLT1 is produced by our mammalian expression system. The target protein is expressed with sequence (Gln16-Pro162) of Human TREML1 fused with a FC tag at the C-terminus.
    Reinheit
    > 95 % as determined by reducing SDS-PAGE.
    Sterilität
    0.2 μm filtered
    Endotoxin-Niveau
    Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
  • Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    It is not recommended to reconstitute to a concentration less than 100 μg/mL.
    Dissolve the lyophilized protein in ddH2O.
    Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
    Buffer
    Lyophilized from a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl, pH 7.4.
    Handhabung
    Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
    Lagerung
    4 °C/-20 °C/-80 °C
    Informationen zur Lagerung
    Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
    Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
    Aliquots of reconstituted samples are stable at < -20°C for 3 months.
    Haltbarkeit
    5 months
  • Target
    TREML1 (Triggering Receptor Expressed On Myeloid Cells-Like 1 (TREML1))
    Andere Bezeichnung
    TREML1 (TREML1 Produkte)
    Synonyme
    GLTL1825, PRO3438, TLT-1, TLT1, dJ238O23.3, 5430401J17Rik, RGD1565175, triggering receptor expressed on myeloid cells 2, triggering receptor expressed on myeloid cells like 1, triggering receptor expressed on myeloid cells-like 1, LOC474898, TREML1, Treml1
    Sub Type
    Fusionprotein
    Hintergrund
    Triggering Receptor Expressed on Myeloid Cells-Like Protein 1 (TREML1) is a single-pass type I membrane protein. TREML1 precursor contains a 15 amino acid signal peptide, a 147 amino acid extracellular domain with an Ig-like V-type (immunoglobulin-like) domain, and 128 amino acid cytoplasmic domain. It can be expressed exclusively in platelets and megakaryocytes (MKs). It is a cell surface receptor that may play a role in the innate and adaptive immune response. TREML1 Sequestered in cytoplasmic vesicles in resting platelets. TREML1 be transported to the cell surface after stimulation by thrombin. Soluble fragments can be released into the serum by proteolysis. The phosphorylated TREML1 can interact with PTPN6 and PTPN11. TREML1 may participate in maintaining vascular hemostasis and regulating coagulation and inflammation at sites of injury.
    Alternative Names: Trem-Like Transcript 1 Protein, TLT-1, Triggering Receptor Expressed on Myeloid Cells-Like Protein 1, TREML1, TLT1
    Molekulargewicht
    42.9 kDa
    UniProt
    Q86YW5
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