Neuroligin 4 Protein (NLGN4) (AA 42-676) (His tag)

Produktnummer ABIN1691472

Produktdetails

Target: Neuroligin 4 (NLGN4)

Protein-Typ: Recombinant

Proteineigenschaft: AA 42-676

Spezies: Human

Quelle: Human Cells

Aufreinigungstag / Konjugat: Dieses Neuroligin 4 Protein ist gelabelt mit His tag.

Verwendungszweck: Recombinant Human Neuroligin 4, X-Linked/NLGN4X (C-6His)

Sequenz: QAQYPVVNTN YGKIRGLRTP LPNEILGPVE QYLGVPYASP PTGERRFQPP EPPSSWTGIR NTTQFAAVCP QHLDERSLLH DMLPIWFTAN LDTLMTYVQD QNEDCLYLNI YVPTEDDIHD QNSKKPVMVY IHGGSYMEGT GNMIDGSILA SYGNVIVITI NYRLGILGFL STGDQAAKGN YGLLDQIQAL RWIEENVGAF GGDPKRVTIF GSGAGASCVS LLTLSHYSEG LFQKAIIQSG TALSSWAVNY QPAKYTRILA DKVGCNMLDT TDMVECLRNK NYKELIQQTI TPATYHIAFG PVIDGDVIPD DPQILMEQGE FLNYDIMLGV NQGEGLKFVD GIVDNEDGVT PNDFDFSVSN FVDNLYGYPE GKDTLRETIK FMYTDWADKE NPETRRKTLV ALFTDHQWVA PAVATADLHA QYGSPTYFYA FYHHCQSEMK PSWADSAHGD EVPYVFGIPM IGPTELFSCN FSKNDVMLSA VVMTYWTNFA KTGDPNQPVP QDTKFIHTKP NRFEEVAWSK YNPKDQLYLH IGLKPRVRDH YRATKVAFWL ELVPHLHNLN EIFQYVSTTT KVPPPDMTSF PYGTRRSPAK IWPTTKRPAI TPANNPKHSK DPHKTGPEDT TVLIETKRDY STELSVDHHH HHH

Produktmerkmale: Recombinant Human Neuroligin 4, X-Linked/NLGN4X is produced by our mammalian expression system in human cells. The target protein is expressed with sequence (Gln42-Ser676) of Human NLGN4X fused with a polyhistidine tag at the C-terminus.

Reinheit: > 95 % as determined by reducing SDS-PAGE.

Sterilität: 0.2 μm filtered

Endotoxin-Niveau: Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Buffer: Lyophilized from a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl, pH 7.4.

Handhabung: Always centrifuge tubes before opening. Do not mix by vortex or pipetting.

Lagerung: 4 °C/-20 °C/-80 °C

Informationen zur Lagerung: Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Haltbarkeit: 3 months

Antigendetails

Target: Neuroligin 4 (NLGN4)

Abstract: NLGN4 Produkte

Synonyme: ASPGX2 Protein, AUTSX2 Protein, HLNX Protein, HNL4X Protein, NLGN4 Protein, nlgn4 Protein, NLGN4X Protein, Nlgn4x Protein, neuroligin 4, X-linked Protein, neuroligin-4, X-linked Protein, NLGN4X Protein, nlgn4x Protein, LOC100714631 Protein

Sub Type: Fusionprotein

Hintergrund: Neuroligin 4, X-Linked (NLGN4X) is a single-pass type I membrane protein that belongs to the type-B carboxylesterase/lipase family. NLGN4X is detected at higher levels in heart and at lower levels in the liver, skeletal muscle, and pancreas. NLGN4X is a putative neuronal cell surface protein involved in cell-cell-interactions. NLGN4X may act as splice site-specific ligands for beta-neurexins. It has been shown that NLGN4X is involved in the formation and remodeling of central nervous system synapses. NLGN4X also interacts with discs, large (Drosophila) homolog 4 (DLG4). Defects in NLGN4X have been associated with autism and Asperger syndrome.
Alternative Names: Neuroligin-4 X-Linked, Neuroligin X, HNLX, NLGN4X, KIAA1260, NLGN4

Molekulargewicht: 72.46 kDa

UniProt: Q8N0W4

Pathways: Cell-Cell Junction Organization, Synaptic Membrane