PDIA4 Protein (Protein Disulfide Isomerase Family A, Member 4) (AA 21-645) (His tag)

Produktnummer ABIN1691444

Produktdetails

Target: PDIA4 (Protein Disulfide Isomerase Family A, Member 4 (PDIA4))

Protein-Typ: Recombinant

Proteineigenschaft: AA 21-645

Spezies: Human

Quelle: Human Cells

Aufreinigungstag / Konjugat: Dieses PDIA4 Protein ist gelabelt mit His tag.

Verwendungszweck: Recombinant Human Protein Disulfide-Isomerase A4/PDIA4 (C-6His)

Sequenz: VAGAEGPDED SSNRENAIED EEEEEEEDDD EEEDDLEVKE ENGVLVLNDA NFDNFVADKD TVLLEFYAPW CGHCKQFAPE YEKIANILKD KDPPIPVAKI DATSASVLAS RFDVSGYPTI KILKKGQAVD YEGSRTQEEI VAKVREVSQP DWTPPPEVTL VLTKENFDEV VNDADIILVE FYAPWCGHCK KLAPEYEKAA KELSKRSPPI PLAKVDATAE TDLAKRFDVS GYPTLKIFRK GRPYDYNGPR EKYGIVDYMI EQSGPPSKEI LTLKQVQEFL KDGDDVIIIG VFKGESDPAY QQYQDAANNL REDYKFHHTF STEIAKFLKV SQGQLVVMQP EKFQSKYEPR SHMMDVQGST QDSAIKDFVL KYALPLVGHR KVSNDAKRYT RRPLVVVYYS VDFSFDYRAA TQFWRSKVLE VAKDFPEYTF AIADEEDYAG EVKDLGLSES GEDVNAAILD ESGKKFAMEP EEFDSDTLRE FVTAFKKGKL KPVIKSQPVP KNNKGPVKVV VGKTFDSIVM DPKKDVLIEF YAPWCGHCKQ LEPVYNSLAK KYKGQKGLVI AKMDATANDV PSDRYKVEGF PTIYFAPSGD KKNPVKFEGG DRDLEHLSKF IEEHATKLSR TKEELLDHHH HHH

Produktmerkmale: Recombinant Human Protein Disulfide-Isomerase A4/PDIA4 is produced by our mammalian expression system in human cells. The target protein is expressed with sequence (Val21-Leu645) of Human PDIA4 fused with a polyhistidine tag at the C-terminus.

Reinheit: > 95 % as determined by reducing SDS-PAGE.

Sterilität: 0.2 μm filtered

Endotoxin-Niveau: Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Rekonstitution: It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Buffer: Supplied as a 0.2 μm filtered solution of 20 mM TrisHCl,150 mM NaCl,10 % Glycerol, pH 7.5.

Handhabung: Always centrifuge tubes before opening. Do not mix by vortex or pipetting.

Lagerung: -80 °C

Informationen zur Lagerung: Store at < -20°C, stable for 6 months after receipt.
Please minimize freeze-thaw cycles.

Haltbarkeit: 6 months

Antigendetails

Target: PDIA4 (Protein Disulfide Isomerase Family A, Member 4 (PDIA4))

Andere Bezeichnung: PDIA4 (PDIA4 Produkte)

Synonyme: LOC100229535, cai, wu:fd20c07, zgc:113965, zgc:136625, zgc:56014, zgc:77773, AI987846, Cai, ERp-72, Erp72, ERP70, ERP72, Erp70, protein disulfide isomerase family A member 4, protein disulfide isomerase family A, member 4, protein disulfide isomerase associated 4, protein disulfide isomerase family A member 4 L homeolog, PDIA4, pdia4, Pdia4, pdia4.L

Sub Type: Fusionprotein

Hintergrund: Protein Disulfide-Isomerase A4 (PDIA4) is an endoplasmic reticulum luminal protein that belongs to the protein disulfide isomerase family. Human PDIA4 is synthesized as a 625 amino acid precursor that contains a 20 amino acid signal sequence, and a 625 amino acid mature chain, including three thioredoxin domains. PDIA4 catalyzes the rearrangement of -S-S- bonds in proteins and is thought to be a deoxycytidine kinase. In addition, PDIA4 serves as a proteases protein disulfide isomerase, phospholipase or an arrangement of these.
Alternative Names: Protein Disulfide-Isomerase A4, Endoplasmic Reticulum Resident Protein 70, ER Protein 70, ERp70, Endoplasmic Reticulum Resident Protein 72, ER Protein 72, ERp-72, ERp72, PDIA4, ERP70, ERP72

Molekulargewicht: 71.7 kDa

UniProt: P13667

Pathways: Thyroid Hormone Synthesis, Cell RedoxHomeostasis