Calumenin (CALU) (AA 20-315) protein (His tag)

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Proteinname
  • 9530075H20Rik
  • Cbp50
  • Rcn
  • crocalbin
  • MGC78837
  • calumenin
  • calumenin L homeolog
  • calumenin homologue
  • CALU
  • Calu
  • calu
  • calu.L
  • calumenin
  • CpipJ_CPIJ002187
  • Tsp_00516
Proteineigenschaft
AA 20-315
13
2
1
1
1
Spezies
Human
12
1
1
1
1
1
1
1
1
Quelle
Mammalian Cells
7
6
2
1
1
1
Protein-Typ
Recombinant
Aufreinigungstag / Konjugat
His tag
Applikation
Functional Studies (Func)
Optionen
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Verwendungszweck Recombinant Human Calumenin/CALU (C-6His)
Sequenz KPTEKKDRVH HEPQLSDKVH NDAQSFDYDH DAFLGAEEAK TFDQLTPEES KERLGKIVSK IDGDKDGFVT VDELKDWIKF AQKRWIYEDV ERQWKGHDLN EDGLVSWEEY KNATYGYVLD DPDPDDGFNY KQMMVRDERR FKMADKDGDL IATKEEFTAF LHPEEYDYMK DIVVQETMED IDKNADGFID LEEYIGDMYS HDGNTDEPEW VKTEREQFVE FRDKNRDGKM DKEETKDWIL PSDYDHAEAE ARHLVYESDQ NKDGKLTKEE IVDKYDLFVG SQATDFGEAL VRHDEFVDHH HHHH
Produktmerkmale Recombinant Human Calumenin/CALU is produced by our mammalian expression system in human cells. The target protein is expressed with sequence (Lys20-Phe315) of Human CALU fused with a polyhistidine tag at the C-terminus.
Reinheit > 95 % as determined by reducing SDS-PAGE.
Sterilität 0.2 μm filtered
Endotoxin-Niveau Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
Sub Type Fusionprotein
Hintergrund Calumenin is a secreted calcium-binding protein that belongs to the CREC family. Calumenin contains six EF-hand domains and is expressed at high levels in the heart, placenta and skeletal muscle. Human Calumenin is synthesized as a 315 amino acid precursor that contains a 19 amino acid signal sequence, and a 296 amino acid mature chain. Calumenin localizes to the endoplasmic reticulum (ER) and sarcoplasmic reticulum (SR) of mammalian tissues which plays a role in ER functions as protein folding and sorting. Calumenin is involved in the regulation of vitamin K-dependent carboxylation of multiple N-terminal glutamate residues. It seems to inhibit gamma-carboxylase GGCX.
Alternative Names: Calumenin, Crocalbin, IEF SSP 9302, CALU
Molekulargewicht 36 kDa
UniProt O43852
Beschränkungen Nur für Forschungszwecke einsetzbar
Format Lyophilized
Rekonstitution It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
Buffer Lyophilized from a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl, pH 7.4.
Handhabung Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
Lagerung 4 °C/-20 °C/-80 °C
Informationen zur Lagerung Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Haltbarkeit 3 months