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DMP1 Protein (Dentin Matrix Acidic phosphoprotein 1) (AA 17-513) (His tag)

DMP1 Spezies: Human Wirt: Human Cells Recombinant > 95 % as determined by reducing SDS-PAGE.
Produktnummer ABIN1691401
$192.50
Zzgl. Versandkosten $45.00
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  • Target Alle DMP1 Proteine anzeigen
    DMP1 (Dentin Matrix Acidic phosphoprotein 1 (DMP1))
    Protein-Typ
    Recombinant
    Proteineigenschaft
    AA 17-513
    Spezies
    • 1
    • 1
    Human
    Quelle
    • 2
    Human Cells
    Aufreinigungstag / Konjugat
    Dieses DMP1 Protein ist gelabelt mit His tag.
    Verwendungszweck
    Recombinant Human Dentin Matrix Acidic Phosphoprotein 1/DMP-1 (C-6His)
    Sequenz
    LPVTRYQNNE SEDSEEWKGH LAQAPTPPLE SSESSEGSKV SSEEQANEDP SDSTQSEEGL GSDDHQYIYR LAGGFSRSTG KGGDDKDDDE DDSGDDTFGD DDSGPGPKDR QEGGNSRLGS DEDSDDTIQA SEESAPQGQD SAQDTTSESR ELDNEDRVDS KPEGGDSTQE SESEEHWVGG GSDGESSHGD GSELDDEGMQ SDDPESIRSE RGNSRMNSAG MKSKESGENS EQANTQDSGG SQLLEHPSRK IFRKSRISEE DDRSELDDNN TMEEVKSDST ENSNSRDTGL SQPRRDSKGD SQEDSKENLS QEESQNVDGP SSESSQEANL SSQENSSESQ EEVVSESRGD NPDPTTSYVE DQEDSDSSEE DSSHTLSHSK SESREEQADS ESSESLNFSE ESPESPEDEN SSSQEGLQSH SSSAESQSEE SHSEEDDSDS QDSSRSKEDS NSTESKSSSE EDGQLKNIEI ESRKLTVDAY HNKPIGDQDD NDCQDGYVDH HHHHH
    Produktmerkmale
    Recombinant Human Dentin Matrix Acidic Phosphoprotein 1/DMP-1 is produced by our mammalian expression system in human cells. The target protein is expressed with sequence (Lys17-Tyr513) of Human DMP1 fused with a 6His tag at the C-terminus.
    Reinheit
    > 95 % as determined by reducing SDS-PAGE.
    Sterilität
    0.2 μm filtered
    Endotoxin-Niveau
    Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
  • Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    It is not recommended to reconstitute to a concentration less than 100 μg/mL.
    Dissolve the lyophilized protein in ddH2O.
    Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
    Buffer
    Lyophilized from a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl, pH 7.4.
    Handhabung
    Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
    Lagerung
    4 °C/-20 °C/-80 °C
    Informationen zur Lagerung
    Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
    Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
    Aliquots of reconstituted samples are stable at < -20°C for 3 months.
    Haltbarkeit
    3 months
  • Target
    DMP1 (Dentin Matrix Acidic phosphoprotein 1 (DMP1))
    Andere Bezeichnung
    Dentin Matrix Acidic Phosphoprotein 1 (DMP1 Produkte)
    Synonyme
    ARHP, ARHR, DMP-1, DENTMAT, AV020965, Dmp, PP, dentin matrix acidic phosphoprotein 1, dentin matrix protein 1, DMP1, Cyan7822_2429, dmp1, Dmp1
    Sub Type
    Fusionprotein
    Hintergrund
    Dentin Matrix Acidic Phosphoprotein 1 (DMP-1) is an extracellular matrix protein and a member of the small integrin binding ligand N-linked glycoprotein family. DMP-1 is expressed in teeth particularly in odontoblast, ameloblast, and cementoblast. DMP-1 is critical for proper mineralization of bone and dentin. DMP-1 may have a dual function during osteoblast differentiation. In the nucleus of undifferentiated osteoblasts, the unphosphorylated form of DMP-1 acts as a transcriptional component for activation of osteoblast-specific genes like osteocalcin. During the osteoblast to osteocyte transition phase, DMP-1 is phosphorylated and exported into the extracellular matrix, where it regulates nucleation of hydroxyapatite. DMP-1 mutations have also been shown to cause rickets hypophosphatemic autosomal recessive type 1 (ARHR1).
    Alternative Names: Dentin Matrix Acidic Phosphoprotein 1, DMP-1, Dentin Matrix Protein 1, DMP1
    Molekulargewicht
    55 kDa
    UniProt
    Q13316
    Pathways
    p53 Signalweg
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