DMP1 Protein (AA 17-513) (His tag)

Produktnummer ABIN1691401

Produktdetails

Target: DMP1 (Dentin Matrix Acidic phosphoprotein 1 (DMP1))

Protein-Typ: Recombinant

Proteineigenschaft: AA 17-513

Spezies: Human

Quelle: Human Cells

Aufreinigungstag / Konjugat: Dieses DMP1 Protein ist gelabelt mit His tag.

Verwendungszweck: Recombinant Human Dentin Matrix Acidic Phosphoprotein 1/DMP-1 (C-6His)

Sequenz: LPVTRYQNNE SEDSEEWKGH LAQAPTPPLE SSESSEGSKV SSEEQANEDP SDSTQSEEGL GSDDHQYIYR LAGGFSRSTG KGGDDKDDDE DDSGDDTFGD DDSGPGPKDR QEGGNSRLGS DEDSDDTIQA SEESAPQGQD SAQDTTSESR ELDNEDRVDS KPEGGDSTQE SESEEHWVGG GSDGESSHGD GSELDDEGMQ SDDPESIRSE RGNSRMNSAG MKSKESGENS EQANTQDSGG SQLLEHPSRK IFRKSRISEE DDRSELDDNN TMEEVKSDST ENSNSRDTGL SQPRRDSKGD SQEDSKENLS QEESQNVDGP SSESSQEANL SSQENSSESQ EEVVSESRGD NPDPTTSYVE DQEDSDSSEE DSSHTLSHSK SESREEQADS ESSESLNFSE ESPESPEDEN SSSQEGLQSH SSSAESQSEE SHSEEDDSDS QDSSRSKEDS NSTESKSSSE EDGQLKNIEI ESRKLTVDAY HNKPIGDQDD NDCQDGYVDH HHHHH

Produktmerkmale: Recombinant Human Dentin Matrix Acidic Phosphoprotein 1/DMP-1 is produced by our mammalian expression system in human cells. The target protein is expressed with sequence (Lys17-Tyr513) of Human DMP1 fused with a 6His tag at the C-terminus.

Reinheit: > 95 % as determined by reducing SDS-PAGE.

Sterilität: 0.2 μm filtered

Endotoxin-Niveau: Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Buffer: Lyophilized from a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl, pH 7.4.

Handhabung: Always centrifuge tubes before opening. Do not mix by vortex or pipetting.

Lagerung: 4 °C/-20 °C/-80 °C

Informationen zur Lagerung: Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Haltbarkeit: 3 months

Antigendetails

Target: DMP1 (Dentin Matrix Acidic phosphoprotein 1 (DMP1))

Andere Bezeichnung: Dentin Matrix Acidic Phosphoprotein 1 (DMP1 Produkte)

Synonyme: ARHP Protein, ARHR Protein, DMP-1 Protein, DENTMAT Protein, AV020965 Protein, Dmp Protein, PP Protein, dentin matrix acidic phosphoprotein 1 Protein, dentin matrix protein 1 Protein, DMP1 Protein, Cyan7822_2429 Protein, dmp1 Protein, Dmp1 Protein

Sub Type: Fusionprotein

Hintergrund: Dentin Matrix Acidic Phosphoprotein 1 (DMP-1) is an extracellular matrix protein and a member of the small integrin binding ligand N-linked glycoprotein family. DMP-1 is expressed in teeth particularly in odontoblast, ameloblast, and cementoblast. DMP-1 is critical for proper mineralization of bone and dentin. DMP-1 may have a dual function during osteoblast differentiation. In the nucleus of undifferentiated osteoblasts, the unphosphorylated form of DMP-1 acts as a transcriptional component for activation of osteoblast-specific genes like osteocalcin. During the osteoblast to osteocyte transition phase, DMP-1 is phosphorylated and exported into the extracellular matrix, where it regulates nucleation of hydroxyapatite. DMP-1 mutations have also been shown to cause rickets hypophosphatemic autosomal recessive type 1 (ARHR1).
Alternative Names: Dentin Matrix Acidic Phosphoprotein 1, DMP-1, Dentin Matrix Protein 1, DMP1

Molekulargewicht: 55 kDa

UniProt: Q13316

Pathways: p53 Signalweg