HMGB2 Protein (High Mobility Group Box 2) (AA 2-209) (His tag)

Produktnummer ABIN1691347

Produktdetails

Target: HMGB2 (High Mobility Group Box 2 (HMGB2))

Protein-Typ: Recombinant

Proteineigenschaft: AA 2-209

Spezies: Human

Quelle: Human Cells

Aufreinigungstag / Konjugat: Dieses HMGB2 Protein ist gelabelt mit His tag.

Verwendungszweck: Recombinant Human High Mobility Group Protein B2/HMGB2 (C-6His)

Sequenz: MGKGDPNKPR GKMSSYAFFV QTCREEHKKK HPDSSVNFAE FSKKCSERWK TMSAKEKSKF EDMAKSDKAR YDREMKNYVP PKGDKKGKKK DPNAPKRPPS AFFLFCSEHR PKIKSEHPGL SIGDTAKKLG EMWSEQSAKD KQPYEQKAAK LKEKYEKDIA AYRAKGKSEA GKKGPGRPTG SKKKNEPEDE EEEEEEEDED EEEEDEDEEV DHHHHHH

Produktmerkmale: Recombinant Human High Mobility Group Protein B2/HMGB2 is produced by our mammalian expression system in human cells. The target protein is expressed with sequence (Gly2-Glu209) of Human HMGB2 fused with a 6His tag at the C-terminus.

Reinheit: > 95 % as determined by reducing SDS-PAGE.

Sterilität: 0.2 μm filtered

Endotoxin-Niveau: Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Buffer: Lyophilized from a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl, pH 7.2.

Handhabung: Always centrifuge tubes before opening. Do not mix by vortex or pipetting.

Lagerung: 4 °C/-20 °C/-80 °C

Informationen zur Lagerung: Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Haltbarkeit: 3 months

Antigendetails

Target: HMGB2 (High Mobility Group Box 2 (HMGB2))

Andere Bezeichnung: HMGB2 (HMGB2 Produkte)

Synonyme: HMG2, C80539, HMG-2, Hmg2, HIGH MOBILITY GROUP BETA 1, HMG BETA 1, NFD02, NFD2, NUCLEOSOME/CHROMATIN ASSEMBLY FACTOR GROUP D 02, NUCLEOSOME/CHROMATIN ASSEMBLY FACTOR GROUP D 2, high mobility group B2, hmgb2, hmgb2l, im:6909096, wu:fa20b02, zgc:101854, high mobility group box 2, high mobility group box 2 S homeolog, high mobility group B2, high mobility group box 2b, HMGB2, Hmgb2, hmgb2.S, hmgb2b

Sub Type: Fusionprotein

Hintergrund: High Mobility Group Protein B2 (HMGB2) belongs to the non-histone chromosomal high-mobility group protein family. Members of this family are chromatin-associated and widely spread in the nucleus of higher eukaryotic cells. HMGB2 contains 2 HMG box DNA-binding domains. It is associated with chromatin and has the ability to bend DNA, preferentially single-stranded DNA. It is shown that HMGB2 is able to efficiently bend DNA and form DNA circles. In addition, HMGB2 is involved in the final ligation step in DNA end-joining processes of DNA double-strand breaks repair and V(D)J recombination.
Alternative Names: High Mobility Group Protein B2, High Mobility Group Protein 2, HMG-2, HMGB2, HMG2

Molekulargewicht: 25.07 kDa

UniProt: P26583

Pathways: Cellular Response to Molecule of Bacterial Origin