CD38 Protein (C-Term, Extracellular Domain)

Produktnummer ABIN1684676

Dieses Recombinant CD38-Protein wird in HEK-293T Cells produziert.

Kurzübersicht für CD38 Protein (C-Term, Extracellular Domain) (ABIN1684676)

Target: CD38

Protein-Typ: Recombinant

Spezies: Maus

Quelle: HEK-293T Cells

Reinheit: > 95 %, as determined by SDS-PAGE and HPLC

Produktdetails

Proteineigenschaft: C-Term, Extracellular Domain

Spezifität: Optimized DNA sequence encoding extracellular domain of mouse CD38 including a C-terminal 6His tag was expressed in HEK293 cells.

Produktmerkmale: Recombinant mouse CD38 is a monomer protein consisting of69 amino acid residue subunits, due to glycosylation migrates as an approximately 45 kDa protein on SDS-PAGE.

Sterilität: 0.2 μm filtered

Endotoxin-Niveau: Endotoxin content was assayed using a LAL gel clot method. Endotoxin level was found to be less than 0.1 ng/µg(1EU/µg).

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS solution, pH7.2

Handhabung: Avoid repeated freeze/thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: The lyophilized protein is stable for at least years from date of receipt at -20 °C. Upon reconstitution, this cytokine can be stored in working aliquots at - 8 °C for one month, or at -20 °C for six months, with a carrier protein without detectable loss of activity.

Haltbarkeit: 12-24 months

Antigendetails

Target: CD38

Hintergrund: Resistin Resistin was identified by screening for genes that are induced during the differentiation of adipocytes but down-regulated in mature adipocytes. Resistin gene expression is induced during the differentiation of adipocytes. Resistin circulates in mouse serum, and its level is increased markedly in obesity. Adipocytes secrete resistin as a unique signaling molecule that may be the hormone potentially linking obesity to type II diabetes, which is characterized by target-tissue resistance to insulin. TNF-alpha is a negative regulator of Resistin gene expression and inhibits Resistin mRNA expression and protein secretion by 70-90 % in 3T3-L1 adipocytes.

UniProt: P56528