IL17RC Protein (C-Term, Extracellular Domain)

Produktnummer ABIN1684628

Dieses Recombinant IL17RC-Protein wird in HEK-293T Cells exprimiert.

Kurzübersicht für IL17RC Protein (C-Term, Extracellular Domain) (ABIN1684628)

Target: IL17RC (Interleukin 17 Receptor C (IL17RC))

Protein-Typ: Recombinant

Spezies: Human

Quelle: HEK-293T Cells

Reinheit: > 98 %, as determined by SDS-PAGE and HPLC

Produktdetails

Proteineigenschaft: C-Term, Extracellular Domain

Spezifität: Optimized DNA sequence encoding extracellular domain of human IL-17RC receptor including a C terminal Human IgG1 Fc tag was expressed in HEK293 cells.

Produktmerkmale: Recombinant IL17RC-Fc is a homodimer protein consisting of 675 amino acid residue subunits, due to glycosylation migrates as an approximately 100kD protein under reducing SDS-PAGE conditions.

Sterilität: 0.2 μm filtered

Endotoxin-Niveau: Endotoxin content was assayed using a LAL gel clot method. Endotoxin level was found to be less than 0.1 ng/µg(1EU/µg).

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: PBS solution, pH7.2

Handhabung: Avoid repeated freeze/thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: The lyophilized protein is stable for at least years from date of receipt at -20 °C. Upon reconstitution, this cytokine can be stored in working aliquots at - 8 °C for one month, or at -20 °C for six months, with a carrier protein without detectable loss of activity.

Haltbarkeit: 12-24 months

Antigendetails

Target: IL17RC (Interleukin 17 Receptor C (IL17RC))

Andere Bezeichnung: IL17RC

Hintergrund: Common gamma chain Interleukin (IL)-2, IL-4, IL-7, IL-9 and IL-15 belong to a family of cytokines whose receptors share the common gamma chain (gamma c). Despite some redundancy, thesecytokines that signal through the gamma c (gamma c cytokines) have essentially distinct and oftencritical effects in normal T-cell development, survival, proliferation and differentiation. Importantly, they have also been implicated,directly or indirectly, in T-cell leukemogenesis.

UniProt: Q8NAC3