PROX1 Protein (partial)

Produktnummer ABIN1589681

Dieses Recombinant PROX1-Protein wird in Escherichia coli (E. coli) produziert.

Kurzübersicht für PROX1 Protein (partial) (ABIN1589681)

Target: PROX1 (Prospero Homeobox 1 (PROX1))

Protein-Typ: Recombinant

Biologische Aktivität: Active

Spezies: Human

Quelle: Escherichia coli (E. coli)

Applikation: Western Blotting (WB)

Reinheit: > 95 % by SDS-PAGE

Produktdetails

Proteineigenschaft: partial

Verwendungszweck: Prox-1 (fragment)

Sequenz: MAEGLSLSLI KSECGDLQDM SEISPYSGSA MQEGLSPNHL KKAKLMFFYT RYPSSNMLKT YFSDVKFNRC ITSQLIKWFS NFREFYYIQM EKYARQAIND GVTSTEELSI TRDCELYRAL NMHYNKANDF EVPERFLEVA QITLREFFNA IIAGKDVDPS WKKAIYKVIC KLDSEVPEIF KSPNCLQELL HE

Spezifität: Chromosomal location:1q32.2-q32.3

Produktmerkmale: Length (aa):192

Anwendungsinformationen

Applikationshinweise: Control for Western Blotting. Biological activity not tested.

Kommentare:

Cytokines & Growth Factors

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Centrifuge vial prior to opening. The lyophilized Prox-1 should be reconstituted in water to a concentration not lower than 50 μg/mL.

Buffer: PBS

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: RT,-20 °C

Informationen zur Lagerung: The lyophilized protein is stable for a few weeks at room temperature, but best stored at -20°C. Reconstituted Prox-1 should be stored in working aliquots at -20°C. Avoid repeated freeze-thaw cycles.

Antigendetails

Target: PROX1 (Prospero Homeobox 1 (PROX1))

Andere Bezeichnung: Prox-1

Hintergrund: Prox-1 is a homeobox gene and acts as a master switch for lymphatic endothelial phenotype. Expression of Prox-1 in blood endothelial cells induces expression of other lymphatic marker genes. Together with Podoplanin, Prox-1 can be used to reliably distinguish lympathic vessels from blood vessels. Prox1 is expressed in CNS, eye, pancreas, liver and heart, and it is one of the most specific and reliable markers for lymphatic endothelial cells. The highly conserved C-terminal part of the homeobox transcription factor Prox1 was produced in E. coli. It was not tested for activity and can be used as positive control e.g. in Western analysis.
Synonyms: PROX1, W117m

Molekulargewicht: 22.35 kDa

Gen-ID: 5629

NCBI Accession: NM_002763, NP_002754

UniProt: Q92786

Pathways: Stem Cell Maintenance, Regulation of Muscle Cell Differentiation