FABP4 Protein (AA 1-132) (His tag)

Produktnummer ABIN1344005

Produktdetails

Target: FABP4 (Fatty Acid Binding Protein 4, Adipocyte (FABP4))

Protein-Typ: Recombinant

Proteineigenschaft: AA 1-132

Spezies: Human

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses FABP4 Protein ist gelabelt mit His tag.

Applikation: SDS-PAGE (SDS)

Verwendungszweck: FABP4 (human) (rec.) (His)

Kreuzreaktivität: Human

Produktmerkmale: Human FABP4 (aa 1-132) is fused at the C-terminus to a His-tag.

Reinheit: >90 % (SDS-PAGE)

Sterilität: Sterile filtered

Endotoxin-Niveau: <1EU/μg purified protein (LAL test).

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: 0.2μm-filtered solution in 55 mM TRIS-Cl, pH 8.2, containing 200 mM NaCl.

Handhabung: After opening, prepare aliquots and store at -20 °C. Avoid freeze/thaw cycles. For maximum product recovery after thawing, centrifuge the vial before opening the cap.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung:

Short Term Storage: +4°C

Long Term Storage: -20°C

Use & Stability: Stable for at least 6 months after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C.

Haltbarkeit: 6 months

Antigendetails

Target: FABP4 (Fatty Acid Binding Protein 4, Adipocyte (FABP4))

Andere Bezeichnung: FABP4 (FABP4 Produkte)

Hintergrund:

Fatty Acid Binding Protein 4, Adipocyte Fatty Acid Binding Protein, ALBP, Adipocyte Lipid Binding Protein

FABP4 is a fatty acid binding protein in adipocytes. Fatty acid binding proteins are a family of small, highly conserved, cytoplasmic proteins that bind long-chain fatty acids and other hydrophobic ligands. FABPs regulate the fatty acid uptake, transport, and metabolism. aP2, the mouse form of FABP4, seems to be central to the pathway that links obesity to insulin resistance. aP2 was shown to be an adipokine linking adipocytes to hepatic glucose production and that neutralizing secreted aP2 may represent an effective therapeutic strategy against diabetes.

Molekulargewicht: ~16kDa (SDS-PAGE)

UniProt: P15090

Pathways: Brown Fat Cell Differentiation