CD2 Protein (CD2) (His tag)

Produktnummer ABIN1098728

Dieses Recombinant CD2-Protein wird in Escherichia coli (E. coli) produziert.

Kurzübersicht für CD2 Protein (CD2) (His tag) (ABIN1098728)

Target: CD2

Protein-Typ: Recombinant

Spezies: Human

Quelle: Escherichia coli (E. coli)

Applikation: SDS-PAGE (SDS)

Reinheit: > 85 % by SDS - PAGE

Produktdetails

Aufreinigungstag / Konjugat: Dieses CD2 Protein ist gelabelt mit His tag.

Anwendungsinformationen

Kommentare:

Synonyms: T-cell surface antigen CD2, SRBC, T11

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/ml (determined by Bradford assay)

Buffer: 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol 0.4 M Urea

Lagerung: 4 °C

Informationen zur Lagerung: Avoid repeated freezing and thawing cycles.

Antigendetails

Target: CD2

Andere Bezeichnung: CD2

Hintergrund: CD2, also known as T-cell surface antigen T11/Leu-5, is a cell adhesion molecule found on the surface of T cells and natural killer (NK) cells. It interacts with other adhesion molecules, such as lymphocyte function-associated antigen-3 (LFA-3/CD58) in humans, or CD48 in rodents, which are expressed on the surfaces of other cells. In addition to its adhesive properties, CD2 also acts as a co-stimulatory molecule on T and NK cells. CD2 is a specific marker for T cells and NK cells, and can therefore be used in immunohistochemistry to identify the presence of such cells in tissue sections. The great majority of T cell lymphomas and leukaemias also express CD2, making it possible to use the presence of the antigen to distinguish these conditions from B cell neoplasms. Recombinant human CD2 protein, fused to His-tag at N-terminus, was expressed in E.coli.

Molekulargewicht: 23.8 kDa (209aa)

NCBI Accession: NP_001758