SH3G2 Protein (His tag)

Produktnummer ABIN1098256

Recombinant SH3G2-Protein exprimiert in Escherichia coli (E. coli).

Kurzübersicht für SH3G2 Protein (His tag) (ABIN1098256)

Target: SH3G2 (Endophilin-A1 (SH3G2))

Protein-Typ: Recombinant

Spezies: Human

Quelle: Escherichia coli (E. coli)

Applikation: SDS-PAGE (SDS)

Reinheit: > 90 % by SDS - PAGE

Produktdetails

Aufreinigungstag / Konjugat: Dieses SH3G2 Protein ist gelabelt mit His tag.

Aufreinigung: purified by chromatography

Anwendungsinformationen

Kommentare:

Synonyms: Endophilin-A1, CNSA2, EEN-B1, SH3D2A, SH3P4

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/ml (determined by Bradford assay)

Buffer: 20 mM Tris-HCl buffer, pH 8.0, 10% glycerol, 1 MM DTT, 50 mM NaCl

Lagerung: 4 °C

Informationen zur Lagerung: Avoid repeated freezing and thawing cycles.

Antigendetails

Target: SH3G2 (Endophilin-A1 (SH3G2))

Andere Bezeichnung: SH3GL2

Hintergrund: SH3GL2 (SH3-domain GRB2-like 2), also known as endophilin-A1, belongs to the endophilin family. It contains a BAR domain and a SH3 domain. Members of the BAR domain protein superfamily are essential elements of cellular traffic. Endophilins are among the best studied BAR domain proteins. They have a prominent function in synaptic vesicle endocytosis (SVE), receptor trafficking and apoptosis, and in other processes that require remodeling of the membrane structure. SH3GL2 a novel tumor suppressor gene in laryngeal squamous cell carcinoma (LSCC), induces apoptosis of tumor cells by regulating intra-cellular signal transduction networks. Recombinant human SH3GL2 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Molekulargewicht: 42.5 kDa (376aa) confirmed by MALDI-TOF

NCBI Accession: NP_003017

Pathways: Neurotrophin Signalübertragung, EGFR Downregulation